Clinical Trials Logo
  1. Home
  2. Colorectal Surgery
  3. NCT05755789

Intermittent Cefoxitin Administration Versus Loading Bolus Followed by Continuous Infusion for the Prevention of Surgical Site Infection in Colorectal Surgery — PROPHYLOXITIN  

Colorectal Surgery Clinical Trial

Official title:
Intermittent Cefoxitin Administration Versus Loading Bolus Followed by Continuous Infusion for the Prevention of Surgical Site Infection in Colorectal Surgery: a Multicentre, Double-blind, Randomized Controlled Clinical Trial

Clinical Trial Summary

The goal of this prospective, multicentre, double-blind, randomized clinical trial is to compare intermittent cefoxitin administration to loading bolus followed by continuous infusion for surgical antibiotic prophylaxis in colorectal surgery. The main objective is to demonstrate the superiority of a loading dose of cefoxitin followed by continuous infusion over standard of care boluses in reducing SSI within 30 days after colorectal surgery

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05755789
Study type Interventional
Source Poitiers University Hospital
Contact Matthieu BOISSON, MD-PhD
Phone +33549444635
Email matthieu.boisson@chu-poitiers.fr
Status Recruiting
Phase Phase 3
Start date June 22, 2023
Completion date June 2025
View Details
See also
  Status Clinical Trial Phase
Terminated NCT03746353 - Early Closure Versus Conventional Closure in Postoperative Patients With Low Anteriresection for Rectal Cancer N/A
Recruiting NCT03560180 - Early Diagnosis of Anastomotic Leakage After Colorectal Surgery: Italian ColoRectal Anastomotic Leakage Study Group.
Completed NCT03357497 - Very Early Mobilization of Colorectal Surgery Patients N/A
Recruiting NCT02143336 - Subcuticular Continuous Suture Versus Skin Staples to Reduce Surgical Site Infections in Colorectal Surgery Patients N/A
Completed NCT02846285 - Causes of Low Digestive Bleeding in Proctology N/A
Completed NCT01547572 - Psychological Preparation for Colorectal Surgery: Impact of Video Education N/A
Completed NCT00731978 - NIRF Trial: Near-Infrared Spectroscopy for Intraoperative Restriction of Fluids Trial N/A
Completed NCT00867958 - Compression Anastomosis Using the CAR™ 27 N/A
Terminated NCT00413127 - Perioperative Protective Effects of Lidocaine Phase 2/Phase 3
Recruiting NCT00498290 - The Protocol of Enhanced Recovery After Surgery in Colorectal Surgery N/A
Not yet recruiting NCT03814681 - Postopoperarive Outcomes After Colorectal Surgery in Europe (euroPOWER)
Completed NCT04040647 - Tolerance of Early Postoperative Mobilization and Ambulation
Completed NCT03012802 - Postoperative Outcomes Within an Enhanced Recovery After Surgery Protocol
Completed NCT03620851 - Enhanced Recovery Program After Colorectal Surgery in Elderly (ERPOLD)
Completed NCT03922113 - Muscle Function After Intensive Care
Completed NCT02947269 - Prucalopride in Postoperative Ileus Phase 3
Recruiting NCT02999217 - Intravenous Iron for Correction of Anaemia After Colorectal Surgery Phase 4
Completed NCT02543190 - System-Wide Improvement for Transitions After Surgery: The SWIFT Post op Program N/A
Completed NCT01220661 - Safety and Efficacy of One Dose Prophylactic Antibiotic in Laparoscopic Colorectal Surgery Phase 2
Recruiting NCT00773981 - Transrectal Vacuum Assisted Drainage: A New Method of Treating Anastomotic Leakage After Rectal Resection Phase 3