Colorectal Surgery Clinical Trial
Official title:
Investigating the Peripheral Perfusion Index; Correlations Between Peripheral and Mesenteric Perfusion in Elective Surgical Patients
NCT number | NCT03395483 |
Other study ID # | H-17004663 |
Secondary ID | |
Status | Completed |
Phase | |
First received | |
Last updated | |
Start date | April 10, 2018 |
Est. completion date | October 1, 2019 |
Verified date | October 2019 |
Source | Hvidovre University Hospital |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
An important goal of haemodynamic monitoring and resuscitation is early detection of
insufficient tissue perfusion and oxygenation. The mesenteric haemodynamic response to
circulatory shock is complex, and diagnosis of bowel ischaemia poses significant difficulty.
Assuming blood flow is diverted from the peripheral tissue and the gastrointestinal tract to
vital organs, during circulatory shock, an objective, simple and non-invasive method of
detecting peripheral tissue perfusion impairment might detect this at an early stage.
The peripheral perfusion index (PPI) reflects changes in peripheral perfusion and laser
doppler flowmetry allows measurement of bowel tissue perfusion.
The aim of this study is to explore the association between changes in peripheral and
intestinal perfusion in patients undergoing elective colorectal surgery exposed to
intraoperative haemodynamic challenges.
Status | Completed |
Enrollment | 30 |
Est. completion date | October 1, 2019 |
Est. primary completion date | October 1, 2019 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years to 120 Years |
Eligibility |
Inclusion Criteria: - Adult - Elective colorectal surgery, low anterior resection of the colon, sigmoid colectomy or right hemicolectomy - Written informed consent Exclusion Criteria: - No consent |
Country | Name | City | State |
---|---|---|---|
Denmark | Anæstesiologisk afdeling, Hvidovre hospital | Hvidovre |
Lead Sponsor | Collaborator |
---|---|
Hvidovre University Hospital |
Denmark,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Peripheral perfusion index and mesenteric perfusion changes from baseline after haemodynamic challenges | Association between PPI and mesenteric perfusion | Perioperatively |
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