Trial of Antibiotic Prophylaxis in Elective Colorectal Surgery

Status Completed

Clinical Trial Summary

To determine the optimal prophylactic antibiotics administration method in elective colorectal surgery

Clinical Trial Description

Use of prophylactic antibiotics in elective colorectal surgery is essential. Although single-dose prophylactic antibiotics are recommended, the efficacy of single-dose cephalosporin without metronidazole and oral antibiotics is not fully proven. We conducted a multicenter randomized trial of single-dose vs. three doses of the second-generation cephalosporin, cefmetazole. ;

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Colorectal Surgery

Clinical Trial Details

NCT number	NCT00292708
Study type	Interventional
Source	National Cancer Center, Japan
Contact
Status	Completed
Phase	Phase 3
Start date	May 2004
Completion date	July 2005

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