Clinical Trials Logo
  1. Home
  2. Colorectal Adenoma
  3. NCT00282386

A Study to Evaluate the Effect of MK0966 (Rofecoxib) on the Recurrence of Colorectal Adenomas (0966-122)

Colorectal Adenoma Clinical Trial

Official title:
A Multicenter, Randomized, Parallel-Group, Placebo-Controlled, Double-Blind Study With In-House Blinding to Determine the Effect of 156 Weeks of Treatment With MK0966 on the Recurrence of Neoplastic Polyps of the Large Bowel in Patients With a History of Colorectal Adenomas

Clinical Trial Summary

This study was to compare the effect of 156 weeks of treatment with MK-0966 (Rofecoxib) versus placebo on the recurrence of colorectal adenomas (growths that occur on the inside (the lining) of the large intestine, also known as the colon) in patients with a history of colorectal adenomas.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00282386
Study type Interventional
Source Merck Sharp & Dohme Corp.
Contact
Status Completed
Phase Phase 3
Start date December 23, 1999
Completion date September 1, 2004
View Details
See also
  Status Clinical Trial Phase
Completed NCT04192565 - A Prospective Investigation of the ColubrisMX ELS System N/A
Completed NCT04516785 - Reducing Colonoscopies in Patients Without Significant Bowel Disease
Recruiting NCT05381792 - Serial Gut Microbiome and Bacterial Gene Markers Changes After Endoscopic Resection of Colorectal Advanced Neoplasia
Withdrawn NCT05606081 - Predicting Risk for Post-polypectomy Colorectal Cancer N/A
Recruiting NCT05576506 - Application of Hyperspectral Imaging Analysis Technology in the Diagnosis of Colorectal Cancer Based on Colonoscopic Biopsy
Active, not recruiting NCT03796884 - Linaclotide in Treating Patients With Stages 0-3 Colorectal Cancer Phase 2
Completed NCT05508503 - A Study on a Blood-based Dual-target Test for CRC Detection
Recruiting NCT02935049 - Evaluation of the Resection of Adenoma and Colic Adenocarcinoma by EMR Piecemeal or EMR/ESD Hybrid Technique N/A
Completed NCT05477836 - Feasibility and Safety of MiWEndo-assisted Colonoscopy N/A
Active, not recruiting NCT05754229 - Accuracy of Real Time Characterization in Artificial Intelligence-assisted Colonoscopy N/A
Active, not recruiting NCT05740137 - Adenoma Detection Rate in Artificial Intelligence-assisted Colonoscopy N/A
Completed NCT03234725 - Analysis of New Endoscopic Features and Variable Stiffness in Colonoscopy: Prospective Randomised Trial
Completed NCT05913453 - Technical Failure During Colorectal Endoscopic Full Thickness Resection (EFTR): The "Through Thick and Thin" Study
Recruiting NCT05261932 - Research on Endoscopic Precision Biopsy.
Completed NCT02521727 - To Investigate Risk of Colorectal Neoplasms in First-degree Relatives of Patients With Non-advanced Adenomas
Completed NCT02226185 - Study of Berberine Hydrochloride in Prevention of Colorectal Adenomas Recurrence Phase 2/Phase 3
Completed NCT00298545 - Effect of Vitamin D and Calcium on Genes in the Colon Phase 1
Completed NCT03268655 - Ginger and Gut Microbiome (GINGER) N/A
Active, not recruiting NCT04952129 - Optimal Selenium for Bowel Polyps (OSCAR) Phase 1
Recruiting NCT04444908 - Development and Validation of an Artificial Intelligence-assisted Strategy Selection System for Colonoscopy Cleaning