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NCT05827471 Clinical Trial

Clinical Study of QSOX1 as a Biomarker for Colon Cancer

Colon Cancer Clinical Trial

Official title:
Clinical Application of Sulfhydryl Oxidase QSOX1 as a New Biomarker of Colon Cancer

Clinical Trial Details — Status: Not yet recruiting

Administrative data
NCT number NCT05827471
Other study ID # QianfoshanHwyq20230305
Secondary ID
Status Not yet recruiting
Phase
First received
Last updated
Start date July 1, 2023
Est. completion date December 31, 2026

Study information
Verified date April 2023
Source Qianfoshan Hospital
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

The goal of this observational study is to determine whether the secreted protein QSOX1 can be used as a molecular marker for early rapid diagnosis and accurate treatment of colon cancer.

Description:

The project mainly selects the tumor group represented by colon cancer and the corresponding healthy people as the control group, with about 100 cases in each of the two groups. Mainly collect blood and tumor tissue samples of patients, detect the expression of QSOX1 in the above samples, and explore the role in the diagnosis and prognosis evaluation of colon cancer.

Recruitment information / eligibility
Status Not yet recruiting
Enrollment 400
Est. completion date December 31, 2026
Est. primary completion date June 30, 2026
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 18 Years to 80 Years
Eligibility Inclusion Criteria: - Colon cancer was confirmed by colonoscopic pathology. - No local or systemic treatment was performed before operation. - Complete clinical data. Exclusion Criteria: - Combined with benign diseases of colon, such as ulcerative colitis, colon adenoma and colon polyp. - Other tumors other than colon cancer.

Study Design

Related Conditions & MeSH terms

Intervention

Diagnostic Test:
• Diagnosis of colon cancer
Clinical diagnosis results

Locations
Country Name City State
n/a

Sponsors (1)
Lead Sponsor Collaborator
Qianfoshan Hospital

Outcome
Type Measure Description Time frame Safety issue
Primary Detection of RNA for early rapid diagnosis of colon cancer. RT-PCR was used to detect the RNA levels of QSOX1 in the tumor and control groups. 6 months
Primary Detection of protein for early rapid diagnosis of colon cancer. Western blotting was used to detect the protein levels of QSOX1 in the tumor and control groups. 6 months
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