Neoadjuvant Therapy for Locally Advanced Colon Cancer

Status Recruiting

Clinical Trial Summary

To determine the Efficacy and Safety of camrelizumab and apatinib combined with chemotherapy (mFOLFOX6) for MSS/pMMR locally advanced colon cancer.

Clinical Trial Description

To determine the rate of tumor regression grade 2-4 at time of radical resection of MSS/pMMR colon cancer following neoadjuvant treatment.To determine the pathologic downstage rates at time of radical resection of colon cancer following neoadjuvant treatment, pathologic complete response (pCR) rates, R0 resection rate, 2 year Disease free survival, OS(overall survival) and adverse events, including perioperative complication and mortality rate. To determine the pathologic downstage rates and pCR rate of radical resection of MSI/dMMR colon cancer. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04625803
Study type	Interventional
Source	Zhejiang University
Contact	Weijia Fang
Phone	+86-571-87235147
Email	weijiafang@zju.edu.cn
Status	Recruiting
Phase	Phase 2
Start date	January 4, 2021
Completion date	November 30, 2025

View Details

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