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ASPIRIN Trial Belgium — ASPIRIN  

Colon Cancer Clinical Trial

Official title:
A Phase III Double-blind Placebo-controlled Randomised Trial of Aspirin on Recurrence and Survival in Colon Cancer Patients

Clinical Trial Summary

The purpose of this study is to determine whether acetylsalicylic acid is effective on the recurrence and survival of colon cancer patients.

Clinical Trial Description

The purpose of this study is to determine the effect of 80mg acetylsalicylic acid (given orally once daily for 5 years) on 5 year overall survival (OS) for stage II and III colon cancer patients of 45 years of age and older. Preclinical, epidemiologic and clinical evidence suggest that acetylsalicylic acid use may reduce overall cancer risk and mortality in colon cancer patients. It is a phase III double blind placebo controlled, randomized trial of adjuvant low-dose acetylsalicylic acid in colon cancer patients. Patients will be stratified at randomization by centre, age (<70 and ≥70 years) chemotherapy use (any versus none) and disease stage. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03464305
Study type Interventional
Source University Hospital, Antwerp
Contact
Status Active, not recruiting
Phase Phase 3
Start date February 22, 2018
Completion date December 31, 2027
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