Colon Cancer Clinical Trial
— OncogrammeOfficial title:
Evaluation of Interest Chemo-oncogramme in Patients With Colonic Adenocarcinoma Stage 4: a Pilot Study
In patients with colonic adenocarcinoma stage 4 which are potentially resectable metastases
(lung and liver metastases), treatment with chemotherapy is necessary but not end in success
in 10% of cases. The development of techniques for administering personalized treatment
becomes necessary for these patients. Thus, in vitro tests on cells from tumors of these
patients and evaluating the effect of chemotherapy on these could be made for each patient.
In France, the company develops Oncomedics these tests.
This is a pilot study that will make a first evaluation under actual conditions of
chimio-oncogramme.
Status | Completed |
Enrollment | 20 |
Est. completion date | March 2013 |
Est. primary completion date | March 2012 |
Accepts healthy volunteers | No |
Gender | Both |
Age group | 18 Years and older |
Eligibility |
Inclusion Criteria: - patient with adenocarcinoma of the colon diagnosed at stage 4 receiving standard therapy - targets must be measurable tumor lesions (RECIST) - patient has not expressed opposition to the use of their residual tumor Exclusion Criteria: - Against-formal indication to an indispensable para-clinical examination of the patient monitoring - Use of chemotherapy, hormone therapy or concomitant radiotherapy - Cons-indication for chemotherapy - Are pregnant, nursing or lack of contraception for women of childbearing age. |
Observational Model: Cohort, Time Perspective: Prospective
Country | Name | City | State |
---|---|---|---|
n/a |
Lead Sponsor | Collaborator |
---|---|
University Hospital, Limoges |
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | In vitro analysis of chemotherapy responses | Evaluate the predictive value of chemo-oncogramme on the patient's response to the same (s) chemotherapy (s) | 7 days | No |
Secondary | quality of life | Evaluate the predictive value of chemo-oncogramme on chemical toxicity and quality of life of patients. | 7 days | No |
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