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NCT01267461 Clinical Trial

Evaluation of the Proliferative Activities of Insulin Analogues in Primary Human Tumor Cells

Colon Cancer Clinical Trial

Clinical Trial Details — Status: Available

Administrative data
NCT number NCT01267461
Other study ID # 0015-10-MMC
Secondary ID
Status Available
Phase N/A
First received December 27, 2010
Last updated August 9, 2012

Study information
Verified date August 2012
Source Meir Medical Center
Contact Ilan Bruchim, MD
Phone 972-9-7472561
Email ilan.bruchim@clalit.org.il
Is FDA regulated No
Health authority Israel: Israeli Health Ministry Pharmaceutical Administration
Study type Expanded Access

Clinical Trial Summary

Recently the general medical literature has become aware that the use of certain long-acting insulin analogues could potentially increase cancer risk.During the last few years the investigators group generated information of both scientific and clinical relevance on the proliferative and anti-apoptotic actions of insulin analogues. The goal of this project is to evaluate the hypothesis that the proliferative and signalling activities elicited by insulin analogues may have a impact on tumor behavior. In this study the investigators will asses the biological actions of insulin analogs in primary tumor cells of endometrial and colon cancer.

Recruitment information / eligibility
Status Available
Enrollment 0
Est. completion date
Est. primary completion date
Accepts healthy volunteers
Gender Female
Age group 18 Years to 90 Years
Eligibility Inclusion Criteria:

- Patients with Endometrial and Colon Cancer

Exclusion Criteria:

Study Design

N/A

Related Conditions & MeSH terms

Intervention

Other:
• Tissue sample from tumor
Endometrial cancer specimens will be obtained from patients operated and treated at the Gynecologic Oncology Unit at Meir Medical Center. Colon cancer specimens will be obtained from patients that underwent colonoscopy at the Gastrointestinal Department at Meir Medical Center.

Locations
Country Name City State
n/a

Sponsors (2)
Lead Sponsor Collaborator
Meir Medical Center Tel Aviv University
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