The Effects of Chiropractic in Adults With Colon Cancer — CCX  

Colon Cancer Stage III Clinical Trial

Official title: The Effects of Chiropractic Care on the Quality of Life and Autonomic Nervous System in Adults With Colon Cancer: a Single-arm Pilot Trial

Status Withdrawn

Clinical Trial Summary

The main objectives of this single-arm pilot trial are to investigate the feasibility of our protocol in terms of 1) recruitment, 2) adherence, 3) tolerability, 4) acceptability and 5) retention. We aim to recruit 20 participants with advanced colon cancer (stage 3-4) who will have assessments of their autonomic nervous system function, carcinoembryonic antigen (CEA) levels, and patient-reported outcomes. Thereafter, patients will be directed to a nearby field clinic to receive twice-weekly cervical assessments & high-velocity, low-amplitude (HVLA) cervical adjustments for a period of 6 weeks. Re-assessments will be performed following 2 weeks and 6 weeks of chiropractic care.

Clinical Trial Description

After providing informed consent, individuals will undergo 6 weeks of chiropractic care. Throughout these 6 weeks there will be three assessments (Day 1, Week 2, and Week 6) that each include the following:

1. Isometric hand grip

2. Postural challenge

3. Patient-reported outcome surveys

4. Off-site blood draw for CEA level testing (only Day 0 and Week 6)

Each assessment will consist of the following recordings:

1. Electrodermal activity [EDA]

2. Impedance cardiography [ICG]

3. Electrocardiogram [ECG] ;

Related Conditions & MeSH terms

• Colon Cancer Stage III
• Colon Cancer Stage IV
• Colonic Neoplasms

• NCT number: NCT05310565
• Study type: Interventional
• Source: Life University
• Status: Withdrawn
• Phase: N/A
• Start date: January 1, 2025
• Completion date: March 1, 2025