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A Study to Evaluate MORF-057 in Adults With Moderately to Severely Active UC — EMERALD-2  

Inflammatory Bowel Diseases Clinical Trial

Official title:
A Phase 2b, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety and Efficacy of 3 Active Dose Regimens of MORF-057 in Adults With Moderately to Severely Active Ulcerative Colitis (EMERALD-2)

Clinical Trial Summary

This is a Phase 2b randomized, double-blind, placebo-controlled study to evaluate the safety and efficacy of three active dose regimens of MORF-057 in adult patients with moderately to severely active Ulcerative Colitis (UC).

Clinical Trial Description

This is a Phase 2b randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of three active dose regimens of MORF-057 plus a placebo regimen in study participants with moderately to severely active UC. After completion of the 12-week Induction Period, participants may be switched to a different active MORF-057 regimen during the Maintenance Period. Those randomized into the placebo group in the Induction Period will be switched to receive an active MORF-057 regimen during the Maintenance Period. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05611671
Study type Interventional
Source Morphic Therapeutic, Inc
Contact Morphic Therapeutic, Inc
Phone 781-996-0955
Email clinicaltrials@morphictx.com
Status Recruiting
Phase Phase 2
Start date October 31, 2022
Completion date July 2025
View Details
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