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Colic clinical trials

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NCT ID: NCT02187614 Completed - Renal Colic Clinical Trials

Efficacy Study of Different Analgesic Options in Kidney Stone Pain Management

Start date: August 2014
Phase: Phase 4
Study type: Interventional

Abdominal pain is one of the most common presentations to an emergency department (ED). Among patients presenting with abdominal pain, a common diagnosis in the Middle East is renal colic (urolithiasis or Kidney stones). As the patients with renal colic writhe around in agonizing pain, the first priority in an ED from a patient's perspective is fast and safe analgesia and to be pain free as early as possible. There are variations in physician preference to choose initial analgesic drug for managing such pain. Commonly used drugs are: - Opioids such as Morphine or Fentanyl - Non steroidal drugs such as Diclofenac, Ketorolac or Brufen - and Paracetamol intravenous injection. A robust evidence in comparison of diclofenac versus morphine and paracetamol is lacking. This study is design to obtain data on efficacy of these three drugs within 30 minutes in a non inferiority trail.

NCT ID: NCT02156596 Completed - Renal Colic Clinical Trials

IV NSAI Versus Nebulized Morphine Analgesia for First-line Renal Colic

NSAIvsNM
Start date: February 2013
Phase: Phase 1
Study type: Interventional

The aim of the investigators study was to evaluate the feasibility, efficacy and safety of nebulized morphine compared with non-steroidal anti-inflammatory (NSAI)intravenously in the management of renal colic. Determine the need for systematic outpatient prescription of NSAI.

NCT ID: NCT01997593 Completed - Colic Clinical Trials

Peritoneal Ropivacaine Infiltration on Postoperative Pain in Children Affected

Start date: November 2013
Phase: Phase 2
Study type: Interventional

The aim of this study was to evaluate the analgesic effect of intraperitoneal infiltration of ropivacaine in children undergoing laparoscopic surgery.

NCT ID: NCT01906762 Completed - Renal Colic Clinical Trials

Comparing the Analgesic Effect of Intravenous Acetaminophen and Morphine on Patients With Renal Colic Pain Reffering to the Emergency Department: A Randomized Controlled Trial

Start date: July 2012
Phase: Phase 2
Study type: Interventional

Kidney stone is one of the most common diseases in every human society and also Iran. What is normally used to treat renal colic pain is Intravenous Opioid with a variety of side effects including hypotension, respiratory depression and apnea, nausea and vomiting. Regarding less complications of Intravenous Acetaminophen, we aimed to compare it with Intravenous Morphine in management of renal colic pain.

NCT ID: NCT01855269 Completed - Crying Clinical Trials

Lactobacillus Reuteri Versus Herbal Drop in the Treatment of Infantile Colic: a Prospective Study

Start date: April 2012
Phase: N/A
Study type: Interventional

The aim was to test the hypothesis that oral administration of Lactobacillus reuteri in a prospective randomized controlled study would improve symptoms of infantile colic.

NCT ID: NCT01849991 Completed - Colic Clinical Trials

Safety and Effect of L. Reuteri on Biomarkers of Inflammation in Healthy Infants With Colic

Start date: September 2013
Phase: Phase 1
Study type: Interventional

This protocol is a study of the effects of Lactobacillus reuteri in 45 healthy infants with colic. The study is being conducted in order to prove treatment dose with probiotic (Lactobacillus reuteri) in a clinical setting is safe in healthy infants with colic.

NCT ID: NCT01761331 Completed - Infantile Colic Clinical Trials

Acupuncture in Infantile Colic - a Three Armed Randomized Multi Center Trial (ACU-COL)

ACU-COL
Start date: January 2013
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this prospective randomized three armed, multi center study is to compare the effect of two types of acupuncture and no acupuncture in 2-8 weeks old infants with infantile colic. Group A will get standardized minimal acupuncture in LI4, group B will get individualized acupuncture in different points according to symptoms and group C will not get acupuncture. Parents (who register the infants crying) and the nurse they meet at the study CHC are blinded.

NCT ID: NCT01546701 Completed - Renal Colic Clinical Trials

Buprenorphine in Acute Renal Colic Pain Management

Start date: March 2011
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine whether sublingual Buprenorphine is as effective as Iv Morphine sulfate on pain control of the patients with acute renal colic in the emergency department.

NCT ID: NCT01541046 Completed - Colic Clinical Trials

Lactobacillus Reuteri DSM 17938 Versus Placebo in the Treatment of Infantile Colic

Start date: November 2011
Phase: Phase 2
Study type: Interventional

Infantile colic is a common medical condition which remains a frustrating problem for parents and health care providers with no clear treatment guidelines. To fill the void in existing literature, we present a protocol to examine whether probiotics are effective in decreasing infantile colic symptoms when compared to placebo treatment. We hypothesize that oral administration of the probiotic L. reuteri DSM 17938 will reduce symptoms of infantile colic in breastfed infants in comparison to placebo. An interim analysis will be conducted after 50 infants randomized to monitor both safety and efficacy.

NCT ID: NCT01532518 Completed - Colic Clinical Trials

Preliminary Efficacy, Safety and Pharmacokinetics Study of Nepadutant in Infant With Feeding Intolerance

Start date: August 2011
Phase: Phase 2
Study type: Interventional

The present pilot study is aimed to obtain preliminary data on the effect of three ascending oral dose levels of nepadutant on the relief of symptoms associated with feeding intolerance. In addition, the assessment of drug exposure (PK assessment) will provide additional information on the dose-effect relationship, thus supporting the dose selection and dosing schedule in the future studies.