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Colic clinical trials

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NCT ID: NCT05323175 Recruiting - Renal Colic Clinical Trials

Erector Spinae Plane (ESP) Block for Renal Colic

Start date: April 25, 2022
Phase: Phase 4
Study type: Interventional

Comparing standard of care to erector spinae plane block for acute renal colic pain.

NCT ID: NCT05271747 Completed - Infant Colic Clinical Trials

Prospective Study to Determine the Factors Influencing Infant Colic

Start date: March 1, 2019
Phase: N/A
Study type: Interventional

Randomized study to determine the effect of a commercialized combination of 2 probiotic strains (Bifidobacterium Longum and Pediococcus pentosaceus) and the impact of feeding type in babies diagnosed with colic under Roma IV criteria when administered for 21 days.

NCT ID: NCT05244291 Completed - Infantile Colic Clinical Trials

Effect of Therapeutic Touch at Different Times on Infantile Colic According to Watson's Theory

Start date: March 25, 2022
Phase: N/A
Study type: Interventional

Aim: The purpose of the study is to determine the effect of therapeutic touch applied to infants with infantile colic at different times on infant colic scale score, crying and sleep duration, according to Watson's theory of human care. Thus, it is aimed to contribute to the development of an effective care approach in eliminating or reducing the symptoms in infants with infantile colic. Method: The study will be conducted as a single-blind, randomized controlled trial. The population of the study will be infants who come to the Pediatrics Outpatient Clinic and are diagnosed as infantile colic according to the evaluation of the pediatrician and have no other health problems. The infants will be divided into three groups as intervention (The first group; the group in which therapeutic touch was applied for one week and the second group; the group in which the therapeutic touch was applied for two weeks) and control groups according to stratified block randomization in the computer environment. After the randomization, therapeutic touch will be applied to the intervention group. No method will be applied to the control group.

NCT ID: NCT05217589 Recruiting - Cramp, Abdominal Clinical Trials

The Influence of Different Mood States and Emotions on the Physiologic, Metabolic, and Perceptual Responses to Feeding Before Exercise

Start date: April 1, 2022
Phase: N/A
Study type: Interventional

Many athletes anecdotally report modifying their nutritional intake before competition in order to avoid gut problems, but no studies have evaluated whether emotional state impacts tolerance to pre-exercise feeding. Therefore, this study will use movie clips (stressful, horror, and funny/amusing) to induce different mood states and emotions, which will be followed by ingestion of food before endurance running on a treadmill. In addition, metabolic and physiologic responses to mood induction will be evaluated.

NCT ID: NCT05198700 Withdrawn - Colic Clinical Trials

The Effect of Probiotics on Symptoms of Infantile Colic

PROCOLIN
Start date: February 8, 2022
Phase: Phase 2
Study type: Interventional

The aim of this study is to evaluate the effects of a probiotic formulation on the daily crying patterns of infants. It is hypothesized that participants given the probiotic formulation will show a significant reduction in daily crying duration compared to participants receiving the placebo.

NCT ID: NCT05150899 Not yet recruiting - Renal Colic Clinical Trials

Role of Antihistaminic in Acute Renal Colic Prevent Pain Recurrence and Expulsion of Ureteric Stone ≤ 1cm

Start date: November 30, 2021
Phase:
Study type: Observational [Patient Registry]

Urolithiasis is one of the most common urological diseases. The risk of stone disease ranges between 5% and 12% worldwide. Ureteric stones account for ≈20% of all urinary tract stones and >70% of the ureteric stones are located in the lower third of the ureter, i.e., distal ureteric stones (DUS). The colicky-type pain in the ureter, an increase in proximal peristalsis through activation of intrinsic ureteral pacemakers may contribute to the perception of pain. Muscle spasm increased proximal peristalsis, local inflammation, irritation, and oedema at the site of obstruction may contribute to the development of pain through chemoreceptor activation and stretching of submucosal free nerve endings. α-adrenergic blockers, anti-inflammatory drugs, antihistaminic and calcium channel blockers, which have a relaxant effect on the ureteric smooth musculature. The presence of histamine receptors in the ureter have been presented in various studies. The histamine-1 (H1) receptors have been shown to have a wide distribution Histamine, which is secreted from the mast cells, causes strong peristaltic contractions in the ureter. alpha adrenoreceptor antagonists (i.e., tamsulosin) have been employed in the treatment of ureteric colic due to smooth muscle relaxation so their potential ability to increase stone passage, reduce pain medication use and reduce urologic interventions. According to the currently accepted view, renal colic management starts with NSAI drugs also NSAI has role in decrease inflammation and oedema and increase expulsion rate . in this study we will compare the use of alpha blocker versus alpha blocker and antihistaminic in management of acute renal colic prevent pain recurrence and increase expulsion rate of ureteric stone ≤ 1cm, with analgesic use in case of acute stage.

NCT ID: NCT05129384 Terminated - Infantile Colic Clinical Trials

The COLIC Study: Colonization of the Infant Gut With B. Infantis EVC001 to Reduce Symptoms of Colic

COLIC
Start date: February 23, 2022
Phase: N/A
Study type: Interventional

To investigate whether B. infantis EVC001 colonization in the infant gut can reduce symptoms of colic

NCT ID: NCT05052476 Completed - Colic Clinical Trials

First Line Dose-efficacy Study of Bactecal® D Liquid for Infant Colic

BACTECOLIC
Start date: April 8, 2022
Phase: N/A
Study type: Interventional

This randomized, open label, dose-response study will be realized at the first line with Bactecal® D Liquid. The objective is to investigate Bactecal® D Liquid in the context of infantile colics. The patients will be randomized into two arms, A and B, in function of the intervention dose. The quality of life of te parents as well as the daily median crying time and the number of daily crying will be assessed.

NCT ID: NCT04983069 Recruiting - Nephropathy Clinical Trials

Neonatal Outcome of Children With Antenatal Colic Hyperechogenicity

COLONECHOGENE
Start date: July 1, 2021
Phase:
Study type: Observational

Fetal colic hyper-echogenicity is a presenting symptoms for cystinuria lysinuria. A few cases of fetuses with dibasic protein intolerance (more complex prognosis) presented with colic hyper-echogenicity antenatal. The aim of this retrospective study is to assess the outcome of fetuses with colic hyperechogenicity in order to increase prenatal counseling

NCT ID: NCT04944628 Completed - Clinical trials for Functional Gastrointestinal Disorders

Observational Prospective Study With Probiotic Supplementation on Infants With FGDI

Start date: August 15, 2018
Phase:
Study type: Observational

This observational prospective study evaluates the safety, tolerability and efficacy of a probiotic formula in infants with functional gastrointestinal disorders (FGDI)