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Colic clinical trials

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NCT ID: NCT02304783 Completed - Renal Colic Clinical Trials

Oral NSAI Versus Paracetamol or Placebo as a Second Line Treatment for Renal Colics

ONSAIP-RC
Start date: January 2014
Phase: Phase 3
Study type: Interventional

Outpatients treatment with NSAI in renal colics has not been well investigated and there is no clear recommendations regarding this matter. The aim of this study is to determine if an oral NSAI treatment is beneficial in patients discharged for the emergency departement after the first line treatment of a renal colic investigating the recurrence of pain, the reconsultation rates and the admissions.

NCT ID: NCT02268955 Completed - Biliary Colic Clinical Trials

Analgesic Efficacy of Intravenous Ibuprofen in Biliary Colic

Start date: September 9, 2014
Phase: N/A
Study type: Interventional

The aim of this study is to assess the analgesic efficacy of intravenous ibuprofen given in the Emergency Department for the treatment of biliary colic. We hypothesize that intravenous ibuprofen will provide a clinically significant drop in self-reported patient pain level as measured by the visual analog scale.

NCT ID: NCT02242292 Completed - Colic Clinical Trials

Study to Evaluate Efficacy and Safety of Oral Doses of Hyoscine Butylbromide for the Treatment of Occasional Abdominal Pain, Cramping, and Discomfort

Start date: April 2006
Phase: Phase 2
Study type: Interventional

Study to determine whether hyoscine butylbromide can provide adequate symptomatic relief of a single episode - defined as lasting not longer than 1 day - and multiple episodes of abdominal pain or discomfort associated with cramping when used as needed

NCT ID: NCT02187614 Completed - Renal Colic Clinical Trials

Efficacy Study of Different Analgesic Options in Kidney Stone Pain Management

Start date: August 2014
Phase: Phase 4
Study type: Interventional

Abdominal pain is one of the most common presentations to an emergency department (ED). Among patients presenting with abdominal pain, a common diagnosis in the Middle East is renal colic (urolithiasis or Kidney stones). As the patients with renal colic writhe around in agonizing pain, the first priority in an ED from a patient's perspective is fast and safe analgesia and to be pain free as early as possible. There are variations in physician preference to choose initial analgesic drug for managing such pain. Commonly used drugs are: - Opioids such as Morphine or Fentanyl - Non steroidal drugs such as Diclofenac, Ketorolac or Brufen - and Paracetamol intravenous injection. A robust evidence in comparison of diclofenac versus morphine and paracetamol is lacking. This study is design to obtain data on efficacy of these three drugs within 30 minutes in a non inferiority trail.

NCT ID: NCT02156596 Completed - Renal Colic Clinical Trials

IV NSAI Versus Nebulized Morphine Analgesia for First-line Renal Colic

NSAIvsNM
Start date: February 2013
Phase: Phase 1
Study type: Interventional

The aim of the investigators study was to evaluate the feasibility, efficacy and safety of nebulized morphine compared with non-steroidal anti-inflammatory (NSAI)intravenously in the management of renal colic. Determine the need for systematic outpatient prescription of NSAI.

NCT ID: NCT02138656 Terminated - Infantile Colic Clinical Trials

CHiropractic for Infantile Colic Study

CHIC
Start date: March 2014
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate whether a course of chiropractic treatment has a significant impact on the natural course of infantile colic, specifically: 1. Do parents of colicky infants randomised to the groups receiving a course of McTimoney chiropractic treatment: - report a significantly greater improvement in hours of crying than those in the control group? - report a significantly greater improvement their own quality of life (anxiety and depression)? - report "resolution" of colic following treatment than the control group? 2. What effect does parental blinding have on parentally-reported symptoms of infantile colic and parental quality of life? The study will also include exploratory investigations to determine whether there are: 1. Any particular groupings of patient characteristics (for example; 'other' presenting symptoms, position in the natural course of colic, age of onset, spinal dysfunction, perinatal factors) that are associated with good or poor outcomes 2. Any particular characteristics of the treatment (e.g. specific adjustments) that are associated with good or poor outcomes.

NCT ID: NCT02094092 Not yet recruiting - Infantile Colic Clinical Trials

Role of ProTectis on Infant Colic and Its Effect on Infant Crying Time and Maternal Mental Health

PRIC-SMM
Start date: May 2014
Phase: N/A
Study type: Interventional

This study will work on hypothetical assumption that compared to the arm supplemented with placebo (control) group; the L reuteri (intervention) group will lower daily crying/fussing time per 24 hours at one month post randomization. And that the L reuteri (intervention) group at 7, 14, 21, days and 1 week after the therapy cessation will have: - Lower crying/fussing time per 24 hours. - Relief from colic pain - Longer sleep duration, - Higher scores on a standardized measure of maternal mental health

NCT ID: NCT01997593 Completed - Colic Clinical Trials

Peritoneal Ropivacaine Infiltration on Postoperative Pain in Children Affected

Start date: November 2013
Phase: Phase 2
Study type: Interventional

The aim of this study was to evaluate the analgesic effect of intraperitoneal infiltration of ropivacaine in children undergoing laparoscopic surgery.

NCT ID: NCT01942928 Recruiting - Infantile Colic Clinical Trials

Cranial Osteopathy in Infantile Colic

Start date: June 2014
Phase: N/A
Study type: Interventional

Background Excessive Crying (Infantile Colic) is one of the most common complaints for which parents seek treatment. These otherwise healthy and well fed infants show no signs of failure to thrive, cry without identifiable cause, fuss a lot and are hard-to-soothe. Objective To explore the feasibility of running a Randomised Controlled Trial (RCT) that investigates the effectiveness of cranial osteopathy in addition to usual National Health Service (NHS) care in infants with colic. Methods Pragmatic randomised controlled trial, involving United Kingdom (UK) osteopaths in private practice and NHS health visitors. Parents of 60 excessively crying infants/infants with colic will be recruited by NHS health visitors. Infants will be included into the study if they are healthy (full-term) and aged 1-7 weeks, diagnosed with excessive crying/infantile colic, and have no co-morbidities. Participants will be randomised into the usual NHS care group or the usual NHS care plus cranial osteopathic intervention group. Usual NHS care will be provided by health visitors and osteopathic treatment will be carried out by experienced osteopaths in private practice. Primary outcome measures are acceptability and feasibility of intervention procedures. Furthermore, changes in the frequency and duration of crying will be documented in a daily crying diary. Parental quality of life will also be assessed. This pilot investigation will provide useful information in order to further develop and adapt the current interventions and trial procedures with a view to a full-scale randomised controlled trial.

NCT ID: NCT01906762 Completed - Renal Colic Clinical Trials

Comparing the Analgesic Effect of Intravenous Acetaminophen and Morphine on Patients With Renal Colic Pain Reffering to the Emergency Department: A Randomized Controlled Trial

Start date: July 2012
Phase: Phase 2
Study type: Interventional

Kidney stone is one of the most common diseases in every human society and also Iran. What is normally used to treat renal colic pain is Intravenous Opioid with a variety of side effects including hypotension, respiratory depression and apnea, nausea and vomiting. Regarding less complications of Intravenous Acetaminophen, we aimed to compare it with Intravenous Morphine in management of renal colic pain.