Effect of a Multistrain Probiotic on Cold Symptoms in Healthy Patients With an History of Upper Airways Infection

Cold Symptom Clinical Trial

Official title: Studio Clinico Randomizzato in Doppio Cieco, Controllato Verso Placebo, a Gruppi Paralleli, Sull'Efficacia Clinica di un Prodotto a Base di Probiotici Nel Migliorare i Comuni Sintomi da Raffreddamento e la Risposta Immunitaria in Adulti Sani - ImmunoCold 2021

Status Recruiting

Clinical Trial Summary

The study is a double-blind randomized clinical trial which aims to evaluate the efficacy of a multi strain probiotic in human adults in controlling and improving cold symptoms and inflammatory response

Clinical Trial Description

Adult subjects (age 18-44) with a history of upper airways infection, will be assigned to placebo or probiotic groups and take either placebo or probiotic dietary intervention for 12 weeks. After that, a 6 weeks follow-up. The answers at: Common Cold Questionnarie (CCQ), Wisconsin Upper Respiratory Symptoms Survey-21 (WURSS-21) and quality of life score (SF-36) will be compared in the two groups. In addition, serological markers (blood count, lymphocyte subpopulation (B, T, T4, T8, NK), IFN-γ and IL-10 levels) will be evaluated over a 18 week period. ;

Related Conditions & MeSH terms

• Cold Symptom
• Nasopharyngitis

• NCT number: NCT05656729
• Study type: Interventional
• Source: Università degli Studi di Ferrara
• Contact: Giacomo Caio, MD, PhD
• Phone: +390532236823
• Email: caigmp@unife.it
• Status: Recruiting
• Phase: N/A
• Start date: December 22, 2022
• Completion date: September 2023