Clinical Trials Logo

Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT05107570
Other study ID # WEU
Secondary ID
Status Completed
Phase N/A
First received
Last updated
Start date May 17, 2021
Est. completion date May 2, 2022

Study information

Verified date July 2022
Source Maastricht University
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

Cold-induced thermogenesis, or the increase in energy expenditure upon cold exposure, indicates metabolic stress, as such, cold-induced thermogenesis may signal an appropriate stimulus to improve metabolic health. Cold acclimation may alter cold-induced thermogenesis due to changes in (non)shivering thermogenesis and blood flow. The main aim of this research is to compare the energy expenditure responses, during a standardised cold stress (~ 9°C air temperature, maximum 1 hour), of Siberian adults with Western European adults. The subjects will be individually matched for age, sex, body mass and height. It was hypothesised that cold-induced thermogenesis will be reduced in the Siberian population.


Read more »

Study Design


Related Conditions & MeSH terms


Intervention

Other:
Cold exposure
Cold air exposure (~ 9°C, maximum 1 hour duration)

Locations

Country Name City State
Netherlands Maastricht University Maastricht

Sponsors (1)

Lead Sponsor Collaborator
Maastricht University

Country where clinical trial is conducted

Netherlands, 

Outcome

Type Measure Description Time frame Safety issue
Primary Cold-induced thermogenesis Energy expenditure with indirect calorimetry 30 min before and during the cold exposure (maximum 1 hour)
Secondary Skin temperature Skin temperature determined with iButtons, measured in °C 30 min before and during the cold exposure (maximum 1 hour)
Secondary Core temperature Core temperature determined with a gastrointestinal pill, measured in °C 30 min before and during the cold exposure (maximum 1 hour)
Secondary Shivering activity Electromyography will be used to measure the electrical activity of 3 skeletal muscles 30 min before and during the cold exposure (maximum 1 hour)
Secondary Substrate oxidation Carbohydrate and fat oxidation will be determined with indirect calorimetry 30 min before and during the cold exposure (maximum 1 hour)
See also
  Status Clinical Trial Phase
Active, not recruiting NCT03541096 - Winter-Swimming and Brown Adipose Tissue Activity in Middel-aged Obese Subjects (WinterBAT). N/A
Recruiting NCT05584527 - Assessment of the Effects of a 24-hour Cold and Heat Exposure on the Factors Influencing Food Intake
Not yet recruiting NCT06424132 - Thermogenic Silencer Regulatory Factors in Humans N/A
Completed NCT04738838 - Oxytocin on Cold Water Task Performance and Recovery Phase 2
Completed NCT05894031 - The Effectiveness of the Wim Hof Method N/A
Recruiting NCT05822141 - Omega-3 Fatty Acids as Regulators of Brown Adipose Tissue During Cold Exposure N/A
Completed NCT01483885 - Comparison of the Analgesic Effects of Acupuncture and Modulated Electroanalgesia in Cold Induced Pain Phase 1/Phase 2
Recruiting NCT04359082 - Cocoa-rich Bioflavanol Supplementation Effects During Cold Exposure N/A
Recruiting NCT06159374 - Effects of Physical Training in Altered Environmental Conditions on Exercise Performance N/A
Active, not recruiting NCT06223087 - Effects of Winter Swimming on Blood Indicators and Oxidative Stress in Males
Completed NCT05545943 - Effects of Calorie Restriction and Cold Stimuli on Health-related Indicators, Cognitive and Motor Functions N/A
Recruiting NCT05076357 - Cold, Appetite and Weight Loss in Individuals With Obesity N/A
Recruiting NCT05464758 - The Effects of Cold Adaptation on Skin Blood Flow, Hand Function, and Comfort in Healthy Adults N/A
Completed NCT03240497 - Effects of Cold Exposure and Breathing Techniques on Immune Response N/A