Cognitive Impairments in Psychotic Disorders

Cognitive Impairment Clinical Trial

Official title: The Timing of Cognitive Impairments in Psychotic Disorders

Status Recruiting

Clinical Trial Summary

Patients with Psychotic disorders (Schizophrenia, Bipolar disorder and Schizoaffective disorder) often suffer from significant cognitive impairments, however how these develop and change over time before and after the first psychotic break is unclear. While there are data by several groups, showing that many future patients have significant cognitive impairments years before the onset of psychosis, many future patients seem to be doing well before the manifestation of psychosis, and decline steeply in functioning after their first psychotic episode. Hence the timing of the onset of cognitive impairment in patients with psychotic disorders requires further exploration. The current study will investigate the timing of cognitive impairment by using IQ tests before and after the first psychotic break

Clinical Trial Description

In this study the investigators aim to use the DAPAR tests (A cognitive assessment which all 17 year old Jewish adolescents in Israel undergo to participate in mandatory military service), which measures intelligence, and is equivalent to the IQ test. The subjects will be persons who had their first psychotic break, at least one year following the DAPAR tests. As part of the study, the participants will re-take the DAPAR tests, after the onset of the psychotic illness. ;

Related Conditions & MeSH terms

• Cognitive Dysfunction
• Cognitive Impairment
• Disease
• Mental Disorders
• Psychotic Disorders

• NCT number: NCT05597579
• Study type: Observational
• Source: Sheba Medical Center
• Contact: Noaz Cohen, MA
• Phone: 972-3-5303325
• Email: noaz.cohen@sheba.gov.il
• Status: Recruiting
• Start date: February 12, 2020
• Completion date: May 1, 2024