Cognitive Impairment Clinical Trial
Official title:
Taiwan Health Promotion Intervention Study for Elders
Objectives: 1-year multidomain health promotion on prevention of physical and cognitive
decline for community-living older people.
Design:
Methods: Randomized controlled trial
Setting:
Five cities(Taipei, Taichung, Kaohsiung, Kinmen, I-Lan) in Taiwan Participants: age 65 or
older community-dwelling prefrail or frail adults Intervention: 1-year multidomain health
promotion (physical, cognitive, nutritional intervention)
Measurements:
Primary outcome includes frailty status and cognitive performance. Secondary outcomes
include depressive symptoms, nutrition assessment, and functional capacity; All the
variables were measured at 0, 6, 12 months. The effect of intervention was investigated by
intention-to-treat analysis.
Eligibility criteria includes: community-dwelling older people aged 65 or older, and those
with confirmed diagnosis of dementia or dependent on activities of daily living were
excluded.
Primary outcome includes frailty status measured by CHS frailty score. general and
sub-domain cognitive performance measured by Montreal Cognitive Assessment (MoCA). Secondary
outcomes include depressive symptoms, nutrition assessment, and functional capacity; which
were evaluated by 5-item Geriatric Depression scale(GDS-5), Mini-nutrition Assessment(MNA),
and instrumental activities of daily living (IADL) individually.
;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT02122198 -
Vascular Mechanisms for the Effects of Loss of Ovarian Hormone Function on Cognition in Women
|
N/A | |
| Recruiting |
NCT04356924 -
Psychological Treatment to Support the Consequences of Cognitive Impairment
|
N/A | |
| Suspended |
NCT05542238 -
The Effect of Acute Exercise on Cardiac Autonomic, Cerebrovascular, and Cognitive Function in Spinal Cord Injury
|
N/A | |
| Terminated |
NCT04493957 -
Evaluation of an Educational Program in the Prevention of the Driving Risks in Patients With Neurocognitive Disorders : ACCOMPAGNE
|
N/A | |
| Recruiting |
NCT04792983 -
Cognition and the Immunology of Postoperative Outcomes
|
||
| Completed |
NCT06029920 -
Influence of Overground Walking on Biomarkers, Cognitive Function, and Quality of Life in Elderly With Mild Cognitive Impairment
|
N/A | |
| Not yet recruiting |
NCT05068323 -
Impact of Interictal Epileptiform Activity on Some Cognitive Domains in Newly Diagnosed Epileptic Patients
|
N/A | |
| Completed |
NCT04426838 -
Cognitive Behavioral Therapy for Insomnia for the Dementia Caregiving Dyad
|
N/A | |
| Completed |
NCT04713384 -
Remote Bimanual Virtual Rehabilitation Post CVD
|
N/A | |
| Recruiting |
NCT06284213 -
Biomarkers for Vascular Contributions to Cognitive Impairment and Dementia Consortium
|
||
| Recruiting |
NCT06053775 -
Non-Invasive Brain Stimulation and Cognitive Training for Depressive Symptomatology Related to Breast Cancer (ONCODEP)
|
N/A | |
| Completed |
NCT03698695 -
A Pharmacodynamics, Safety, and Pharmacokinetics Study of THN201 Versus Donepezil in Healthy Male Volunteers
|
Phase 1 | |
| Not yet recruiting |
NCT05552729 -
Effects of Different Doses of Vitamin D on Cancer-related Cognitive Impairment in Patients With Gastrointestinal Tumors
|
Phase 1/Phase 2 | |
| Recruiting |
NCT03268109 -
COGnitive ImpairmenT in Older HIV-infected Patients ≥ 65 Years Old
|
||
| Completed |
NCT03301402 -
Air Purifier to Improve Endothelial Function and Carotid Intima Thickness
|
N/A | |
| Completed |
NCT03187353 -
IMProving Executive Function Study
|
Phase 4 | |
| Completed |
NCT05395559 -
Prevalence and Recognition of Cognitive Impairment in Hospitalized Patients: a Flash Mob Study
|
||
| Recruiting |
NCT04907565 -
Impact of Obesity on Post-operative Cognitive Dysfunction: Role of Adipose Tissue
|
||
| Recruiting |
NCT05030285 -
Telehealth Psychotherapy for Anxiety in Persons With Cognitive Impairment
|
N/A | |
| Recruiting |
NCT04897334 -
Transcranial Direct Current Stimulation and Rehabilitation to Ameliorate Impairments in Neurocognition After Stroke
|
N/A |