Cognitive Dysfunction Clinical Trial
The purpose of this study is to determine whether the administration of physostigmine in combination with sedation for colonoscopy can minimize the cognitive decline at the time of hospital discharge
Status | Not yet recruiting |
Enrollment | 160 |
Est. completion date | July 2011 |
Est. primary completion date | July 2011 |
Accepts healthy volunteers | No |
Gender | Both |
Age group | 18 Years to 80 Years |
Eligibility |
Inclusion Criteria: - Over18 years old - ASA I-III - Fluency in Hebrew, Russian, or Arabic - Absence of serious hearing or vision impairment Exclusion Criteria: - History of head trauma, neurological diseases, alcoholism, drug abuse, consumption of psychotropic drugs or antidepressants - Heart failure (NYHA > 3) - Liver failure - Respiratory problems (asthma, etc.) |
Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Outcomes Assessor), Primary Purpose: Prevention
Country | Name | City | State |
---|---|---|---|
Israel | Hasharon Hospital, Rabin Medical Center | Petah Tiqva |
Lead Sponsor | Collaborator |
---|---|
Rabin Medical Center |
Israel,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Cognitive functioning assessed by standard neuropsychological tests | At time of hospital discharge following colonoscopy procedure | No |
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