Comparison of Three Motor-cognitive Training Programs

Status Completed

Clinical Trial Summary

Understanding how to delay age-related physical and mental declines is an issue for aging research. It has been shown that isolated aerobic, coordination and cognitive training improve brain functions and cognitive performances. Moreover, the combination of them leads to greater effects. Different combination modalities are possible: training programs demanding cognitive resources within the activity performed in a natural environment like Nordic Walking (or Tai chi, Dance...); or as in a conceptually-grounded circuit training where training components are systematically combined and their intensity controlled. The aim of this study is to compare three training programs: a Nordic walking one (NW), and two conceptual grounded, circuits training (CT-c; CT-fit). CT-c implemented by dual-task (DT) exercises, while CT-fit characterized by cognitive charge embodied in the movements through the use of technology. An improvement in physical, motor, and cognitive functions is expected by all three groups. However, our primary hypothesis is that the CT-fit will impact executive functions more. 45 healthy independent living community dwellers participants aged 65 to 80 will be recruited. Participants will be included after a general medical examination (geriatric screening and cycle-ergometer maximal effort test). The main exclusion criteria are signs of cognitive impairment, (MMSE <26/30), and physical impairments. Participants will be randomly divided into the 3 groups (NW, CT-c, CT-fit): The training program will last 8 weeks, 1 hour 3 times a week. Pre and post-tests will include cognitive assessment (MoCA; TMT; Stroop task, Happy Neuron™ working memory test, Rey Complex Figure copy task and dual-task capacities through the DT-OTMT); motor fitness assessment (Bipedal upright standing, Unipedal balance test, walking speed and size of the base of support, Timed Up & Go, Chair sit and reach test and Four square stepping test) and physical assessment (10 m incremental shuttle walking test, maximal handgrip force, 30s chair rise stand). Improving cognitive functions by adding new technology embodied in a systematically combined training (exergame), would result to be the best solution to optimize training for aging people.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04504643
Study type	Interventional
Source	Aix Marseille Université
Contact
Status	Completed
Phase	N/A
Start date	October 1, 2022
Completion date	April 30, 2023

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT03228446` - The Effects of Attentional Filter Training on Working Memory	N/A
Completed	`NCT04033419` - Memantine for Prevention of Cognitive Decline in Patients With Breast Cancer	Phase 2
Terminated	`NCT05199142` - A Study to Evaluate the Safety, Tolerability, and Pharmacodynamics of SDI-118 in Elderly Male and Female Study Participants With Cognitive Decline	Phase 1
Active, not recruiting	`NCT05290233` - Time Restricted Eating Plus Exercise for Weight Management	N/A
Terminated	`NCT03337282` - Incidence and Characteristics of Postoperative Cognitive Dysfunction in Elderly Quebec Francophone Patients
Unknown status	`NCT00696514` - Vitamin B12 and Folic Acid Supplementation for Preventing Fractures in Elderly People	Phase 1
Completed	`NCT00110604` - The Effect of Folic Acid on Atherosclerosis, Cognitive Performance and Hearing	N/A
Recruiting	`NCT06245005` - Preoperative Cognitive Reserve in Older Surgical Patients: A Feasibility Study
Recruiting	`NCT05014399` - Cognitive Impairment in Colorectal Cancer Patients Receiving Cytotoxic Chemotherapy
Active, not recruiting	`NCT05586750` - Statins in Reducing Events in the Elderly Mind (STAREE-Mind) Imaging Substudy	Phase 4
Completed	`NCT04386902` - Evaluation of Cognitive State Using Neurosteer EEG System
Recruiting	`NCT06070818` - Healthy Body & Mind Program for Older Adults Living With Osteoarthritis and Cognitive Decline	N/A
Completed	`NCT01669915` - A Large Randomized Trial of Vitamin D, Omega-3 Fatty Acids and Cognitive Decline	N/A
Completed	`NCT02814526` - Exercise in Adults With Mild Memory Problems	N/A
Not yet recruiting	`NCT05928078` - A Home-based e-Health Intervention in the Elderly: MOVI-ageing	N/A
Not yet recruiting	`NCT06252376` - Effects of Blood Pressure on Cognition and Cerebral Hemodynamics in PD	N/A
Recruiting	`NCT06318377` - Peanuts and Neurocognitive / Cardiovascular Health in Black Individuals	N/A
Recruiting	`NCT03839784` - Building a Platform for Precision Anesthesia in the Geriatric Surgical Patient
Completed	`NCT04537728` - My Healthy Brain: Preserving and Promoting Brain Health Through Evidence-based Practices	N/A
Active, not recruiting	`NCT03370796` - Group Reminiscence Therapy for Elderly People With Cognitive Decline in Institutional Context	N/A

Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Comparison of Three Motor-cognitive Training Programs — EXECO

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms