Cognitive Decline Clinical Trial
Official title:
Cognitive Trajectories and Clinical Outcomes in Elderly Patients With Preoperative Cognitive Dysfunction
Verified date | May 2016 |
Source | Zhongda Hospital |
Contact | Jian-jun Yang, Dr. |
Phone | 13357739238 |
yjyangjj[@]126.com | |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
Preexisting cognitive impairment, such as mild cognitive impairment, is common in many elderly patients who undergoing major surgeries. Accumulating evidence has demonstrated that preexisting cognitive impairment is associated with increased mortality, increased incidence of postoperative complications, decreased quality of life, and worse outcomes. However, few studies have evaluated the relationship between preexisting cognitive impairment and cognitive trajectories and clinical outcomes.
Status | Recruiting |
Enrollment | 500 |
Est. completion date | August 2018 |
Est. primary completion date | May 2018 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 65 Years and older |
Eligibility |
Inclusion Criteria: - Inclusion criteria were persons 65 years and older undergoing an elective operation on the general, noncardiac thoracic, urologic, and vascular surgical services. Exclusion Criteria: - Patients with vision or hearing impairment who could not visualize pictures or hear instructions associated with the delirium assessments and patients who could not provide informed consent. |
Country | Name | City | State |
---|---|---|---|
China | Zhongda Hospital | Nanjing | Jiangsu |
Lead Sponsor | Collaborator |
---|---|
Zhongda Hospital |
China,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Cognition changes | Cognitive function was assessed at baseline before the elective operation and one year in all subjects using the Mini-Cog test by a member of a trained research team. | 1 year |
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT03228446 -
The Effects of Attentional Filter Training on Working Memory
|
N/A | |
Completed |
NCT04033419 -
Memantine for Prevention of Cognitive Decline in Patients With Breast Cancer
|
Phase 2 | |
Terminated |
NCT05199142 -
A Study to Evaluate the Safety, Tolerability, and Pharmacodynamics of SDI-118 in Elderly Male and Female Study Participants With Cognitive Decline
|
Phase 1 | |
Active, not recruiting |
NCT05290233 -
Time Restricted Eating Plus Exercise for Weight Management
|
N/A | |
Terminated |
NCT03337282 -
Incidence and Characteristics of Postoperative Cognitive Dysfunction in Elderly Quebec Francophone Patients
|
||
Unknown status |
NCT00696514 -
Vitamin B12 and Folic Acid Supplementation for Preventing Fractures in Elderly People
|
Phase 1 | |
Completed |
NCT00110604 -
The Effect of Folic Acid on Atherosclerosis, Cognitive Performance and Hearing
|
N/A | |
Recruiting |
NCT06245005 -
Preoperative Cognitive Reserve in Older Surgical Patients: A Feasibility Study
|
||
Recruiting |
NCT05014399 -
Cognitive Impairment in Colorectal Cancer Patients Receiving Cytotoxic Chemotherapy
|
||
Active, not recruiting |
NCT05586750 -
Statins in Reducing Events in the Elderly Mind (STAREE-Mind) Imaging Substudy
|
Phase 4 | |
Completed |
NCT04386902 -
Evaluation of Cognitive State Using Neurosteer EEG System
|
||
Recruiting |
NCT06070818 -
Healthy Body & Mind Program for Older Adults Living With Osteoarthritis and Cognitive Decline
|
N/A | |
Completed |
NCT01669915 -
A Large Randomized Trial of Vitamin D, Omega-3 Fatty Acids and Cognitive Decline
|
N/A | |
Completed |
NCT02814526 -
Exercise in Adults With Mild Memory Problems
|
N/A | |
Not yet recruiting |
NCT06252376 -
Effects of Blood Pressure on Cognition and Cerebral Hemodynamics in PD
|
N/A | |
Not yet recruiting |
NCT05928078 -
A Home-based e-Health Intervention in the Elderly: MOVI-ageing
|
N/A | |
Recruiting |
NCT06318377 -
Peanuts and Neurocognitive / Cardiovascular Health in Black Individuals
|
N/A | |
Recruiting |
NCT03839784 -
Building a Platform for Precision Anesthesia in the Geriatric Surgical Patient
|
||
Completed |
NCT04537728 -
My Healthy Brain: Preserving and Promoting Brain Health Through Evidence-based Practices
|
N/A | |
Active, not recruiting |
NCT03370796 -
Group Reminiscence Therapy for Elderly People With Cognitive Decline in Institutional Context
|
N/A |