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The Effects of Hydration on Gut Health and Thinking — WatUP  

Cognitive Change Clinical Trial

Official title:
Investigating the Effects of Increased Water Consumption on Markers of Gut Health, Microbiota, and Executive Function

Clinical Trial Summary

The central hypothesis is that improving hydration through increased water consumption will change the relative abundance of mucolytic bacteria found in the stool. Therefore the specific aims are 1) to quantify intervention effects on fecal microbiota relative abundance and plasma lipopolysaccharide binding protein, 2) observe the effects of the intervention on bowel frequency and signs/symptoms of gastrointestinal stress, and 3) to investigate relations between executive function and hydration status.

Clinical Trial Description

A single arm 3-week hydration intervention will be employed where participants increase their water consumption to 2 (F) or 2.5(M) liters per day which is approximately 70% of the AI for daily water consumption. Pre-test and follow-up measures of fecal microbiota, urinary hydration status, cognitive function, circulating markers, and dietary intake will be assessed at baseline and at 3-week follow up via laboratory visits. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05315531
Study type Interventional
Source University of Illinois at Urbana-Champaign
Contact
Status Completed
Phase N/A
Start date August 23, 2021
Completion date July 29, 2022
View Details
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