Cost Effective Treatment for Dually Diagnosed Homeless

Cocaine Dependence Clinical Trial

Official title:

Cost Effective Treatment for Dually Diagnosed Homeless

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00368524
• Other study ID #: F920822004
• Secondary ID: 1R01DA011789
• Status: Completed
• Phase: N/A
• Start date: November 2001
• Est. completion date: November 2005

Study information

• Verified date: August 2006
• Source: University of Alabama at Birmingham
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

This randomized controlled trial examined whether an abbreviated treatment using abstinence contingency management for housing and work/training (CM, n=103) with cocaine dependent, non-psychotic, dually diagnosed homeless persons, would show non-inferior outcomes compared to the full treatment (CM+, n=103). It was hypothesized that CM+ would show superior abstinence and retention outcomes, but that CM, with components derived from previously effective behavioral day treatment, would obtain non-inferior outcomes, defined as 75% or more of those observed for the full treatment (CM+) during active treatment months 1-6. The CM+ included all CM components but added behavioral day treatment that included voucher reinforcement of $7.50-15.00, for objective weekly therapeutic goal attainment in five domains of functioning: drug dependence, homelessness, unemployment, non-drug related recreational activities, and behavioral, health, or mental health problems. Abstinence was assessed by observed urine specimen collection and weekly testing weeks 1-52, and randomly, bi-monthly for months 13-18. Abstinence, homelessness, employment and other outcomes were also assessed at baseline, 2, 6, 12, and 18 months.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 160
• Est. completion date: November 2005
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria: McKinney Act criteria for homelessness; DSM IV diagnosis for Cocaine Dependence; self-reported use within the last 2 weeks; psychological distress indicated by score of 70 on 1 or more Brief Symptom Inventory scales; willingness to participate; no plans to move from Birmingham area for 18 months;

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Exclusion Criteria: cognitive impariment precluding informed consent; requiring immediate inpatient medical treatment

Related Conditions & MeSH terms

• Cocaine Dependence
• Cocaine-Related Disorders
• Homelessness
• Mental Disorder
• Mental Disorders
• Psychotic Disorders
• Unemployment

Intervention

Behavioral:
• contingency management and behavioral day treatment

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
University of Alabama at Birmingham

References & Publications (1)

Milby JB, Schumacher JE, Wallace D, Freedman MJ, Vuchinich RE. To house or not to house: the effects of providing housing to homeless substance abusers in treatment. Am J Public Health. 2005 Jul;95(7):1259-65. doi: 10.2105/AJPH.2004.039743. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	abused drug abstinence measured by observed urine specimen testing weeks 1-52, and bimonthly months 13-18
Secondary	abstinence, housing, employment and other outcomes at 0, 2, 6, 12 and 18 months.