Clinical Trials Logo
  1. Home
  2. Cocaine Abuse
  3. NCT02393599

Study to Assess Potential Interactions Between Intravenous Cocaine and Oral Lorcaserin

Cocaine Abuse Clinical Trial

Official title:
Phase 1, Double-Blind, Placebo-Controlled, Parallel-Group Study to Assess Potential Interactions Between Intravenous Cocaine and Oral Lorcaserin

Clinical Trial Summary

The primary objective of this study is to determine if there are significant interactions between oral lorcaserin treatment concurrent with 20 and 40 mg intravenous (i.v.) cocaine infusions by measuring adverse events (AEs) and cardiovascular responses including heart rate (HR), blood pressure (BP), and electrocardiogram (ECG) (including QTc).

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Safety Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator), Primary Purpose: Diagnostic

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02393599
Study type Interventional
Source National Institute on Drug Abuse (NIDA)
Contact
Status Completed
Phase Phase 1
Start date May 2015
Completion date September 2015
View Details
See also
  Status Clinical Trial Phase
Completed NCT01601743 - Exercise as a Behavioral Treatment for Cocaine Dependence N/A
Completed NCT00217997 - Impulsivity, Brain Function, and Substance Abuse Treatment in Cocaine Dependent Individuals N/A
Completed NCT00842517 - Long Term Maintenance of Drug Abstinence Phase 1
Completed NCT00227903 - Therapeutic Substance Abuse Treatment in Pregnancy - 1 Phase 2
Terminated NCT00142883 - The Effects of GABA Enhancing Medications on Individuals Addicted to Cocaine - 3 N/A
Completed NCT02563769 - Clavulanic Acid (CLAV) and Cocaine Interaction Safety Study Phase 1
Completed NCT01651377 - Pramipexole as a Treatment for Cocaine Dependence Phase 1
Recruiting NCT00439049 - Substance Abuse Pre-Treatment Screening Study
Completed NCT00249457 - Employment-based Reinforcement to Motivate Drug Abstinence in the Treatment of Drug Addiction. - 2 N/A
Completed NCT01401270 - Prize Contingency Management for Cocaine-Dependent Methadone Patients N/A
Completed NCT00350610 - Computer-Based Training in Cognitive Behavior Therapy Phase 1
Recruiting NCT06177860 - Clinical and Atherosclerotic Characteristics of Patients With ACS Associated With Cocaine Use
Completed NCT02141620 - n-Acetylcysteine and Cocaine Phase 0
Recruiting NCT00218023 - Medications for Stopping Cocaine Dependence and Preventing Relapse Phase 2
Completed NCT00218075 - Behavioral Therapy Combined With Carbidopa/Levodopa for the Treatment of Cocaine Dependence Phase 2
Recruiting NCT05857852 - Low-Intensity Focused Ultrasound for Cocaine Use Disorder N/A
Completed NCT00606801 - Galantamine Effects on Cognitive Function in Abstinent Cocaine Users N/A
Completed NCT00292123 - Combined Behavioral and Pharmacologic Treatment of Polydrug Abuse Phase 1
Completed NCT00318760 - Effect of Clonidine on Responses to Imagery Scripts Phase 1
Completed NCT01651364 - A Pilot Study of Cabergoline for the Treatment of Cocaine Dependence Phase 1