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n-Acetylcysteine and Cocaine

Cocaine Dependence Clinical Trial

Official title:
Motivation for Cocaine and Non-Drug Reinforcers: Targeting Glutamate Homeostasis

Clinical Trial Summary

This study will determine the initial efficacy, safety and tolerability of n-acetylcysteine as a pharmacotherapy for cocaine dependence. A rigorous, inpatient human laboratory study will be conducted in which the subjective, physiological and reinforcing effects of cocaine are evaluated during maintenance on placebo and n-acetylcysteine.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Pharmacodynamics Study, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Caregiver, Outcomes Assessor), Primary Purpose: Basic Science

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02141620
Study type Interventional
Source University of Kentucky
Contact
Status Completed
Phase Phase 0
Start date May 2014
Completion date April 2016
View Details
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