Clinical Trials Logo
  1. Home
  2. CMV
  3. NCT00872703

Does Normal Brain Imaging Predict Normal Neurodevelopmental Outcome in Fetuses With Proven Cytomegalovirus Infection?

Ultrasound Clinical Trial

Official title:
Does Normal Brain Imaging Predict Normal Neurodevelopmental Outcome in Fetuses With Proven Cytomegalovirus Infection?

Clinical Trial Summary

Cytomegalovirus (CMV) is the largest member of the virus family Herpesviridae that infects almost all humans at some point in their lives (Ross, 2004). Congenital CMV infection is most likely to occur when the mother experiences a primary infection during pregnancy, and it is much less common in cases of reactivation of the disease or infection by a different CMV strain (Boppana 1999, Endres 2001). The prevalence of congenital CMV infection varies between 0.15-2.2% (Ross 2004, Ross 2006, Malm 2007). While most infants born with congenital CMV infection are asymptomatic, 10 to 15% show clinical findings at birth (Ross 2004).

It is generally agreed that congenital CMV infection, whether it is symptomatic or not, is a major risk factor for perceptual deficits. However, its influence on children's future neuropsychological functioning is less well established. Symptomatic congenital CMV infection is a major risk factor for poor developmental outcome (Williamson 1982, Kylat 2006, Dollard 2007), but the available data regarding neuropsychological outcome for asymptomatic children is extremely diverse (Conboy 1986, Ivarson 1997, Kashdan 1998, Temple 2000, Zhang 2007).

We evaluated the neuropsychological outcome of children with congenital cytomegalovirus (CMV) infection and normal consecutive fetal neurosonographic examinations and determined whether Magnetic Resonance Imaging (MRI) provided additional information in these cases.

Clinical Trial Description

n/a

Study Design

Observational Model: Case Control, Time Perspective: Retrospective

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00872703
Study type Observational
Source Wolfson Medical Center
Contact
Status Completed
Phase N/A
Start date January 2008
Completion date February 2009
View Details
See also
  Status Clinical Trial Phase
Completed NCT04546867 - Establishing a Sonographic Based Algorithm to Verify Pancreatic Stent Position Placed to Prevent Post-ERCP Pancreatitis Before Endoscopic Removal N/A
Not yet recruiting NCT06053892 - AR US Versus sUS or Fluoroscopic Injections for Shoulder Punction N/A
Completed NCT05013476 - Tele-Ultrasound: VIrtual Hands-on Education for Novice Users N/A
Completed NCT04554472 - Usefulness of Intraoperative Ultrasound in a Volar Plate Distal Radius Fixation
Not yet recruiting NCT06456957 - Fetal Abdominal Subcutaneous Tissue Thickness in Prediction of Fetal Weight in Term Pregnant Women
Not yet recruiting NCT04550793 - Using Shear Wave Ultrasound Elastography for Follow up After Anti-spastic Intervention Among Stroke Patients
Completed NCT03563196 - Diagnosis Of Pulmonary Complications After Cardiac Surgery In Children
Completed NCT01666626 - Ultrasound Stiffness Imaging in Crohn's Disease N/A
Active, not recruiting NCT04928560 - Diagnosis of Superficial Lymphadenopathy
Recruiting NCT05938790 - Point of Care Ultrasound in Obstetric Triage N/A
Completed NCT06098105 - Laparoscopic vs Ultrasound-Guided Transversus Abdominis Plane Block vs Laparoscopic Intraperitoneal Instillation of Local Anesthetic in Pediatrics N/A
Recruiting NCT02834585 - Magnetic Resonance Imaging or Ultrasound in Soft Tissue Tumors (MUSTT) N/A
Completed NCT02661607 - Point of Care Echocardiography Versus Chest Radiography for the Assessment of Central Venous Catheter Placement N/A
Completed NCT01519167 - Open-Label, Safety Study Evaluating the Use of Dexmedetomidine in Pediatric Subjects Undergoing Procedure-Type Sedation Phase 4
Completed NCT04612816 - Live Stream of Ultrasound in Prehospital Medical Care
Active, not recruiting NCT06195488 - Gastric Ultrasound in Diabetic Patients
Recruiting NCT06199856 - Assessment System for Sarcopenia Based on Ultrasonographic Data
Not yet recruiting NCT04563897 - Prospective Multicenter Study on Clinical Application of Sonazoid in Liver Tumor
Completed NCT04574258 - Prospective Multicenter Study on Clinical Application of Sonozoid in Thyroid Tumor
Completed NCT04124770 - Neck Position and Ultrasound Landmark of Cricothyroid Membrane