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Clinical Trial Summary

A randomized, double-blinded, two-way crossover study investigating the headache inducing capabilities of PACAP-38 in patients with cluster headache. Forty-five patients (15 episodic patients in cluster, 15, episodic patients in remission and 15 chronic cluster headache patients) are expected to participate. Each patients will on two separate study days in a randomized way receive an infusion of PACAP-38 and VIP over 20 minutes followed by an observation period of 70 minutes. Blood samples for investigation of VIP, PACAP38; CGRP, NSE, Histamine and Tryptase will be drawn at fixed time-points during experiment.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT03814226
Study type Interventional
Source Danish Headache Center
Contact Agneta Snoer, MD
Phone + 45 26274040
Email agneta.henriette.snoer.02@regionh.dk
Status Recruiting
Phase N/A
Start date January 1, 2018
Completion date May 5, 2020

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