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Clubfoot clinical trials

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NCT ID: NCT04737083 Not yet recruiting - Clubfoot Clinical Trials

CGH Array in Bilateral Clubfoot

Start date: January 31, 2021
Phase:
Study type: Observational

In prenatal diagnosis of isolated bilateral clubfoot our team propose genetic analysis: a CGH-array. We want to study the rate of aberrations in these cases.

NCT ID: NCT04693065 Active, not recruiting - Clubfoot Clinical Trials

Pronostic Factors of Long Term Outcome in Patients With Clubfoot Treated by the Ponseti Method

Start date: January 1, 2020
Phase:
Study type: Observational

We aim at finding prognostic factors of long term (after growth) function outcome in patient with clubfoot treated by ponseti method, based on a very complete prospective recording of treatment variables and outcome

NCT ID: NCT04564430 Recruiting - Trigger Finger Clinical Trials

Clonidine for Tourniquet-related Pain in Children

CLOTCH
Start date: March 1, 2021
Phase: Phase 4
Study type: Interventional

This study is designed as a randomized, placebo-controlled, double-blinded, clinical trial with two parallel groups. This study investigates the association between a single dose of the drug, Clonidine, and the total amount of opioid administered under and 24 hours after surgery in children undergoing orthopedic limb surgery with the use of tourniquet. The investigators hypothesize that administration of clonidine to children undergoing limb surgery with the use of inflatable tourniquets would reduce post-procedural pain. This study is a pilot to obtain an effect size. Based on this the investigators will calculate a sample size for the main trial enabling us to reach a power of 0.8 with a significans level of 0.05.

NCT ID: NCT04212663 Not yet recruiting - Recurrent Clubfoot Clinical Trials

A Study on the Treatment of Recurrent Clubfoot With the Tendon Release of Musculi Tibialis Posterior

Start date: February 1, 2020
Phase: N/A
Study type: Interventional

The musculi tibialis posterior can adduct the foot, so releasing the tedon of the muscle can help to correct the deformity of the forefoot adduction.

NCT ID: NCT03953430 Completed - Clubfoot Clinical Trials

Gait Analysis in Children With Clubfoot Treated With Tibialis Anterior Tendon Transfer

Start date: January 1, 2014
Phase:
Study type: Observational

Patients with clubfoot treated with the Ponseti method and undergoing Tibialis Anterior tendon transfer from a prospective database are evaluated using gait analysis including the Oxford foot model and compared to a group of healthy children.

NCT ID: NCT03853811 Terminated - Clinical trials for Congenital Talipes Equinovarus

Customized Orthosis for Children With Clubfoot

Start date: April 17, 2019
Phase: N/A
Study type: Interventional

This study will examine the use of a novel customized Ankle Foot Orthosis (AFO), created using 3D scanning, with children being treated for clubfoot. The AFO is inserted in the standard Mitchell shoe during bracing, following Ponseti casting. The investigators hypothesize that following Ponseti casting, the implementation of customized AFOs with Ponseti bracing will improve patient compliance and functional outcomes as well as lead to fewer relapses in comparison to the standard bracing with Mitchell shoes.

NCT ID: NCT03749265 Not yet recruiting - Clubfoot Clinical Trials

Rate Of Residual Clubfoot Deformity With Correlation To Absence Of Peroneus Tertius Muscle

Start date: December 2018
Phase:
Study type: Observational

Rate Of Residual Clubfoot Deformity With Correlation To Absence Of Peroneus Tertius Muscle , A Prospective Study.

NCT ID: NCT03671863 Completed - Clubfoot Clinical Trials

Children Born With Club Feet

CBCF
Start date: January 1, 2014
Phase:
Study type: Observational

Clubfoot is one of the most common birth defects, with a prevalence in Europe estimated between 1 and 4.5 for 1000 live birth. It is useful to distinguish the forms of isolated clubfoot, and the forms related to others morphological abnormalities (complex clubfoot). For the complex forms, the clubfoot can be integrated in a syndromic association, be the consequence of a serious harm of the central nervous system, be associate to a genetic musculo-skeletal disease or wether be associated to a karyotype abnormality. In those cases, the prognosis depends more about the associated morphological abnormalities that can be the beginning of a severe disability or incompatible with life or any anomaly of the karyotype that clubfoot itself. In case of several morphological abnormalities, to propose invasive samples with realization of a karyotype and chromosome analysis with CGH array is a consensual attitude. What the investigators should recommended to the parents in case of isolated form is less obvious and the question of antenatal investigations can not be answered clearly in the literature. Thus, the management of these patients may vary from one CPDP to another. This study project will make it possible to analyze the management offered to patients whose fetuses have club feet and to study the results of the various examinations carried out in order to adapt the prenatal counselling and to define the best diagnostic strategy to propose to the future parents.

NCT ID: NCT03580746 Withdrawn - Clubfoot Clinical Trials

Comparison of Ponseti Method Versus Older Treatments in Talipes Equinovarus Through Gait Analysis and Clinical Results

Start date: September 2014
Phase:
Study type: Observational

There are many different treatments of congenital talipes equinovarus. At our institution, the investigators use the Ponseti method with manipulation and immobilization of the foot. In this study the investigators should like to demonstrate the better outcome in clinical results and in gait analysis of patients treated with the Ponseti method, compared to the 'older' methods of taping and posteromedial release.

NCT ID: NCT03501043 Completed - Clinical trials for Equinovarus; Acquired

Assessment of Gait After Dysport Treatment

Start date: June 11, 2018
Phase: Phase 4
Study type: Interventional

This pilot study will aim to understand the potential benefit of the assessment of walking using video slow motion for muscle selection and the development of an image catalogue guide of the potential results of injection of abobotulinumtoxinA by comparing foot postures before and after injection. The objective is to evaluate the use of video assessment to improve muscle selection for the injection of botulinum toxin A to improve walking outcomes. Primary outcomes include: self-selected velocity (SSV), maximal velocity (MV) and symmetry of walking. Secondary outcomes include: passive range of motion (PROM), Modified Ashworth Scale (MAS) and the Tardieu Scale (TS). Fifteen persons post stroke or TBI over age 18 with equinovarus foot deformity who are able to ambulate will be included in the study. Dysport 1000 to 1500 units will be used to be distributed on the basis of clinical indication to ankle plantar flexors (gastrocnemius and soleus), tibialis posterior and long toe flexors. The duration of subjects' participation is 4-6 weeks.