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Rituximab Plus Venetoclax in Combination With Zandelisib in Subjects With CLL — CORAL  

CLL Clinical Trial

Official title:
A Phase 2 Single-Arm, Open-Label Study to Assess the Safety and Efficacy of Rituximab Plus Venetoclax in Combination With Zandelisib in Subjects With Relapsed or Refractory Chronic Lymphocytic Leukemia - The CORAL Study

Clinical Trial Summary

A Phase 2 study of Zandelisib with Venetoclax (VEN) and Rituximab (R) in subjects with Relapsed/Refractory CLL.

Clinical Trial Description

This is an open label Phase 2 clinical study of Zandelisib with Venetoclax (VEN) and Rituximab (R) in subjects with R/R CLL. VEN and R will be administered per standard of care. Subjects must have histologically confirmed relapsed/refractory CLL and received ≥1 lines of prior therapy A total 42 subjects will be enrolled and treated with zandelisib in combination with VEN + R. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05209308
Study type Interventional
Source MEI Pharma, Inc.
Contact
Status Withdrawn
Phase Phase 2
Start date November 22, 2022
Completion date March 15, 2023
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