Neuromuscular Electrical Stimulation After Lung Transplantation

Status Recruiting

Clinical Trial Summary

Clinical Trial Description

Pulmonary transplantation aims to increase patient survival and quality of life in relation to functional aspects. It is observed that the decrease in muscle mass and pulmonary changes are some complications that can be found in the post-transplant patient due to immobility. Thus, NMES rehabilitation is of paramount importance for the recovery of the individual, both in the functional aspects, and in the minimization in the time of hospitalization.The objective of this study was to evaluate the effects of NMES on the thickness and strength of the quadriceps femoris muscle, pulmonary function, endothelial function, functional capacity, muscle biochemical markers, arterial blood gas analysis and water balance of patients after lung transplantation through a randomized clinical trial. Patients will be randomized into two groups: EENM group: will receive the application of NMES associated with physiotherapy and control group: who will receive only the physiotherapy protocol of the HCPA. The NMES training will be applied once a day (30 minutes of application per session, increasing one minute every two days and reducing the OFF time), until the discharge of the Intensive Care Unit (ICU). The patient will continue with the application also in the Hospitalization Units of the HCPA and Irmandade da Santa Casa de Misericórdia de Porto Alegre until the hospital discharge. The following outcomes will be evaluated: thickness and strength of the quadriceps muscle, pulmonary function, endothelial function, functional capacity, mobility, muscle biochemical markers, arterial blood gas analysis, water balance and length of stay in the ICU, time and success of weaning from invasive mechanical ventilation and survival rate through medical records analysis. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03788876
Study type	Interventional
Source	Hospital de Clinicas de Porto Alegre
Contact	Graciele Sbruzzi
Phone	+555133085857
Email	graciele.sbruzzi@ufrgs.br
Status	Recruiting
Phase	N/A
Start date	May 3, 2019
Completion date	November 1, 2020

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT02581111` - Naloxone for Optimizing Hypoxemia Of Lung Donors	Phase 2/Phase 3
Recruiting	`NCT02177916` - Patient Education Study to Determine Knowledge Acquisition in Patients Preparing to Undergo Lung Transplantation	N/A
Not yet recruiting	`NCT01394835` - Safety and Efficacy of Inhaled Alpha-1 Antitrypsin in Preventing Bronchiolitis Obliterable Syndrome in Lung Transplant Recipients	Phase 2
Not yet recruiting	`NCT01162148` - Pulmonary Rehabilitation and Inspiratory Muscle Training (IMT) for Patients Following Lung Transplantation	N/A
Completed	`NCT01204970` - Confocal Laser Micro-endoscopy in Chronic Obstructive Pulmonary Disease (COPD) and Lung Transplant Recipients	N/A
Active, not recruiting	`NCT00980967` - Predictive Factors for Chronic Rejection in Lung Transplant Recipients: COLT Study	N/A
Completed	`NCT00531921` - Effects of Donor and Recipient Genetic Expression on Heart, Lung, Liver, or Kidney Transplant Survival	N/A
Recruiting	`NCT00163696` - Multi Breath Nitrogen Washout (MBNW) as a Measure of Small Airway Function in Patients With Respiratory Disease	N/A
Completed	`NCT00177684` - Pharmacokinetic Profiles of Inhaled Lipid Complex Amphotericin B (Abelcet ®)	Phase 3
Completed	`NCT00163891` - Comparison of Two Chest Physiotherapy Protocols in Lung Transplant Recipients	N/A
Completed	`NCT03668483` - Relation Between Muscle Strength With Exercise Capacity and Dyspnea in LTx	N/A
Not yet recruiting	`NCT02855372` - Impact of the Age Difference Between the Donor and Recipient on the Morbidity and Mortality After Lung Transplantation. Study on a National Multicenter Cohort (COLT)	N/A
Completed	`NCT01211509` - Montelukast in Bronchiolitis Obliterans Syndrome	Phase 4
Completed	`NCT01212406` - Vitamin D in Bronchiolitis Obliterans Syndrome	Phase 4
Not yet recruiting	`NCT00808600` - Empowerment of Lung and Heart-lung Transplant Patients	N/A
Completed	`NCT00553397` - Live Lung Donor Retrospective Study	N/A
Completed	`NCT00402805` - Improving the Humoral Response to Influenza Vaccine in Lung Transplant Recipients by an Intradermal Strategy	Phase 4
Terminated	`NCT00235651` - Abelcet Radiotagging Protocol: Inhaled Lipid Complex Abelcet® in Lung Transplant Recipients	Phase 3
Completed	`NCT00701922` - Surveillance Study of Viral Infections Following Lung Transplantation	N/A
Active, not recruiting	`NCT02936505` - Clinical Study Evaluating Two Treatment Protocols for Immunosuppressive Drugs. Looking at 3-year Incidence of CLAD.	N/A