Clinical Symptoms Clinical Trial
— DROSOALLERGAllergy is a very common problem and can be a handicap in everyday life, specially when symptoms occur at work place. Some persons working with drosophila developed respiratory symptoms. Investigators tried to analyze if these manifestations could be due to a specific allergy to drosophila.
| Status | Completed |
| Enrollment | 12 |
| Est. completion date | February 2015 |
| Est. primary completion date | February 2015 |
| Accepts healthy volunteers | No |
| Gender | Both |
| Age group | 18 Years to 68 Years |
| Eligibility |
Inclusion Criteria: - major males or females (aged <68) who work in laboratory with drosophila in Montpellier (France) - clinical symptoms in presence of drosophila - The subject must be affiliated to a social security scheme - Provision of informed consent prior to any study specific procedures Exclusion Criteria: - The patient has indicated against (or incompatible drug combination) concerning the implementation of a prick test - antihistamine cure in progress - Inability to understand the nature and goals of the study and / or communication difficulties with the investigator - No affiliation to a French social security recipient or not such a scheme - Major protected by law (guardianship, curator or under judicial protection) - deprivation of liberty by judicial or administrative decision - Increased likelihood of non compliance to the protocol or abandonment under study - pregnancy or breastfeeding |
Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Prevention
| Country | Name | City | State |
|---|---|---|---|
| France | Hôpital Arnaud de Villeneuve | Montpellier |
| Lead Sponsor | Collaborator |
|---|---|
| University Hospital, Montpellier |
France,
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | Number of participants with positive prick test to drosophila | Prick tests : measuring the size of the skin reaction (wheal) after prick tests with drosophila. A wheal measuring more than 4 millimeters in diameter sign a sensitization to drosophila. Then, a blood sample is collected in order to measure specific drosophila IgE rate | The day of inclusion | Yes |
| Secondary | Survey to analyse risk factors for allergy to drosophila | analysis of professional (attended institute, time from start working with drosophila, type of animal manipulation (species, living, dead, DNA, protein) use of protection,) or personal factors (age, gender, others allergies, treatment used) which could lead to allergic reaction to drosophila | The day of inclusion | Yes |