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Clinical Trial Summary

Gonadotropin-releasing hormone analogue (GnRH-a) is a synthetic decapeptide compound which can down-regulate pituitary function causing a temporary low estrogen state. Since endometriosis is an estrogen-dependent disease, the use of long-acting GnRH-a can control the growth of endometriosis by inhibiting ovary function.Some scholars have found that, for adenomyosis patients who received a super long protocol (pretreatment of long-acting GnRH-a for 1-2 months) in IVF treatment, the pregnancy outcome is comparable to that of the controls with normal uterus. Thus, the aim of this study is to compare the clinical pregnancy rate in patients treated with GnRH-a for 1, or 2 months.


Clinical Trial Description

n/a


Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Outcomes Assessor), Primary Purpose: Treatment


Related Conditions & MeSH terms


NCT number NCT03006406
Study type Interventional
Source The First Affiliated Hospital of Zhengzhou University
Contact Huijuan Kong, M.D.
Phone 86-371-67966161
Email [email protected]
Status Recruiting
Phase N/A
Start date January 2016
Completion date January 2018

See also
  Status Clinical Trial Phase
Completed NCT03350646 - Does the Volume of the Embryo Culture Medium During Embryo Transfer Affects the IVF Outcomes? N/A
Completed NCT04175990 - IVF Outcome Following Progestogen Ovarian Stimulation Phase 1
Completed NCT03162315 - The Value of Progesterone for the Timing of the Embryo Transfer in IVF/ICSI: a Prospective Randomised Trial N/A
Recruiting NCT02496754 - The Application of a New Ovarian Stimulation Protocol in IVF N/A
Terminated NCT00737984 - Improving the Pregnancy Rate With Endometrial Sampling Before Intrauterine Insemination N/A