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Clinical Deterioration clinical trials

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NCT ID: NCT04026555 Completed - Clinical trials for Clinical Deterioration

Realtime Streaming Clinical Use Engine for Medical Escalation

ReSCUE-ME
Start date: June 18, 2019
Phase: N/A
Study type: Interventional

The escalation of care for patients in a hospitalized setting between nurse practitioner managed services, teaching services, step-down units, and intensive care units is critical for appropriate care for any patient. Often such "triggers" for escalation are initiated based on the nursing evaluation of the patient, followed by physician history and physical exam, then augmented based on laboratory values. These "triggers" can enhance the care of patients without increasing the workload of responder teams. One of the goals in hospital medicine is the earlier identification of patients that require an escalation of care. The study team developed a model through a retrospective analysis of the historical data from the Mount Sinai Data Warehouse (MSDW), which can provide machine learning based triggers for escalation of care (Approved by: IRB-18-00581). This model is called "Medical Early Warning Score ++" (MEWS ++). This IRB seeks to prospectively validate the developed model through a pragmatic clinical trial of using these alerts to trigger an evaluation for appropriateness of escalation of care on two general inpatients wards, one medical and one surgical. These alerts will not change the standard of care. They will simply suggest to the care team that the patient should be further evaluated without specifying a subsequent specific course of action. In other words, these alerts in themselves does not designate any change to the care provider's clinical standard of care. The study team estimates that this study would require the evaluation of ~ 18380 bed movements and approximately 30 months to complete, based on the rate of escalation of care and rate of bed movements in the selected units.

NCT ID: NCT03915925 Completed - Pulmonary Embolism Clinical Trials

Short-term Clinical Deterioration After Acute Pulmonary Embolism

Start date: September 30, 2018
Phase:
Study type: Observational

This is a prospective, observational, multicenter cohort study to compare right ventricular dysfunction dependent and independent prognostic models for short-term serous adverse events in patients who are diagnosed with pulmonary embolism in the emergency department. Clinical endpoints are assessed at days 1-5. A thirty-day follow-up phone call is conducted to obtain further clinical endpoints and a quality of life assessment.

NCT ID: NCT03912701 Recruiting - Clinical trials for Early Clinical Deterioration

Early Warning Systems, Risk of Early Clinical Deterioration

Start date: August 1, 2019
Phase:
Study type: Observational

Primary purpose of the study was to evaluate the relationship between "NEWS" and "VIEWS" scores of patients who were screened retrospectively, early clinical deterioration, return to intensive care and morbidity / mortality.

NCT ID: NCT03910777 Recruiting - Early Warning Score Clinical Trials

Usefulness of Early Warning Systems in Detecting Early Clinical Deterioration After Intensive Care Discharge

Start date: August 1, 2019
Phase:
Study type: Observational [Patient Registry]

The VitalPac Early Warning Score (VIEWS) scoring system, developed by Prytherch et al., Is an early warning system that aims to predict the first 24-hour mortality in emergency patients. National early warning score (NEWS) is another early warning scoring system recommended by the Royal College of Physicians in London to detect early clinical deterioration in hospitalized patients. The aim of this study was to determine the early clinical deterioration after ICU and hence the rate of admission to intensive care and to evaluate whether these two scoring systems can be used to determine early clinical deterioration in intensive care early discharge.