Cleft Lip and Palate Clinical Trial
Official title:
Short Term Efficiency of Presurgical Vacuum Formed Nasoalveolar Molding Aligners in Infants With Bilateral Cleft Lip and Palate Compared With Conventional Grayson Acrylic Formed Nasoalveolar Molding Appliances: A Randomized Clinical Trial
Newborns with bilateral cleft lip/ palate will be treated pre-surgically by either presurgical vacuum-formed nasoalveolar molding aligners VF (NAM) or conventional Grayson acrylic formed nasoalveolar molding appliances in order to evaluate their effect on the maxillary arch.
The aim of this trial is to evaluate and compare the short-term effect of VF (NAM) aligners with conventional Grayson appliances at 2 stages T1 (Before NAM therapy), and T2 (After NAM therapy) as regards maxillary arch changes. Newborns with Bilateral cleft lip/ palate will be allocated randomly into two groups: the first group will receive presurgical vacuum-formed nasoalveolar molding aligners while the second group will receive conventional Grayson acrylic formed nasoalveolar molding appliances. The follow-up period will be 4-6 months till surgical lip closure. The changes in the maxillary arch will be assessed by digital maxillary models. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Enrolling by invitation |
NCT05876169 -
How Does Orthognathic Surgery Affect Jaw and Neck Motor Function?
|
N/A | |
| Recruiting |
NCT04455035 -
DynaCleft® Effects on Soft Tissues and on Quality of Life for Incomplete Unilateral Cleft Lip Infants
|
N/A | |
| Not yet recruiting |
NCT05031039 -
Skeletal and Dental Maturational Stages in a Sample of Egyptian Subjects With Cleft Lip and Palate Deformity
|
||
| Recruiting |
NCT03839290 -
Development of the Palate in Bilateral Orofacial Cleft Newborns One Year After Early Neonatal Cheiloplasty
|
||
| Recruiting |
NCT04771156 -
Ketorolac in Palatoplasty
|
Phase 4 | |
| Completed |
NCT04725370 -
Characterization of Cleft Lip and Palate Conditions in Guatemala
|
||
| Enrolling by invitation |
NCT02702869 -
Allied Cleft & Craniofacial Quality-Improvement and Research Network (ACCQUIREnet)
|
||
| Active, not recruiting |
NCT05971914 -
Alveolar Cleft Hard- and Soft Tissue Reconstruction With an Autogenous Tooth Derived Particulate Graft
|
N/A | |
| Completed |
NCT03708406 -
Otologic and Rhinologic Outcomes in Children With Clef Palate
|
||
| Recruiting |
NCT06105099 -
Effect of Performance-specific Cleft Speech Intervention and Long-term Learning in Children With a Cleft Palate
|
N/A | |
| Completed |
NCT06075069 -
Evaluation of the Effect of Prosthetic Management for Congenital Cleft Lip and Palate Infants on the Middle Ear Function
|
N/A | |
| Completed |
NCT04384276 -
Weigh Easy: Simplifying Home Weight Monitoring for Infants
|
N/A | |
| Recruiting |
NCT04619030 -
Augmented Reality (AR): The Future of "Patient Information Leaflets
|
N/A | |
| Recruiting |
NCT03065686 -
Identification of Genetic Factors Implicated in Orofacial Cleft Using Whole Exome Sequencing
|
N/A | |
| Completed |
NCT02845193 -
Effect of Novel Nasoalveolar Molding Techniques on Parents' Satisfaction and Short Term Treatment Outcomes in Unilateral Cleft Lip and Palate Infants: A Randomized Controlled Trial
|
N/A | |
| Completed |
NCT03308266 -
Electromyographic Analysis of the Masticatory Muscles in Cleft Lip and Palate Children With Temporomandibular Disorders
|
N/A | |
| Completed |
NCT01932164 -
Use of Mesenchymal Stem Cells for Alveolar Bone Tissue Engineering for Cleft Lip and Palate Patients
|
N/A | |
| Not yet recruiting |
NCT06411444 -
Effect of Different Nasal Stent Designs With Nasoalveolar Molding Appliance
|
N/A | |
| Not yet recruiting |
NCT06292234 -
Patient Specific Implant Versus Miniplates for Advancement of Hypoplastic Maxilla
|
N/A | |
| Recruiting |
NCT05081258 -
Influence of Presurgical Orthodontic Molding on the Growth of Newborns With Unilateral Cleft Lip Palate
|
N/A |