Tissue Engineered Constructs for Alveolar Cleft Repair

Status Completed

Clinical Trial Summary

Description of the research question

In children undergoing unilateral alveolar cleft reconstruction, would stem cells carried on collagen scaffold provide bone of a good quality and quantity if compared to autogenous bone grafting?

Objective of the study:

• Research hypothesis

The tissue engineered constructs will provide sufficient bone of a good quality and quantity if compared to autogenous bone graft in children undergoing unilateral alveolar cleft reconstruction.

- The objectives

The primary objective:

Assessment of bone volume (quantity) which will be provided by tissue engineered constructs compared to that provided by autogenous bone for maxillary alveolar cleft reconstruction.

The secondary objective:

Assessment of bone density (quality) which will be provided by tissue engineered constructs compared to that provided by autogenous bone for maxillary alveolar cleft reconstruction.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03563495
Study type	Interventional
Source	Cairo University
Contact
Status	Completed
Phase	N/A
Start date	February 2015
Completion date	September 2017

View Details

See also
Status	Clinical Trial	Phase
Enrolling by invitation	`NCT05876169` - How Does Orthognathic Surgery Affect Jaw and Neck Motor Function?	N/A
Recruiting	`NCT04455035` - DynaCleft® Effects on Soft Tissues and on Quality of Life for Incomplete Unilateral Cleft Lip Infants	N/A
Not yet recruiting	`NCT05031039` - Skeletal and Dental Maturational Stages in a Sample of Egyptian Subjects With Cleft Lip and Palate Deformity
Recruiting	`NCT03839290` - Development of the Palate in Bilateral Orofacial Cleft Newborns One Year After Early Neonatal Cheiloplasty
Recruiting	`NCT04771156` - Ketorolac in Palatoplasty	Phase 4
Completed	`NCT04725370` - Characterization of Cleft Lip and Palate Conditions in Guatemala
Enrolling by invitation	`NCT02702869` - Allied Cleft & Craniofacial Quality-Improvement and Research Network (ACCQUIREnet)
Active, not recruiting	`NCT05971914` - Alveolar Cleft Hard- and Soft Tissue Reconstruction With an Autogenous Tooth Derived Particulate Graft	N/A
Completed	`NCT03708406` - Otologic and Rhinologic Outcomes in Children With Clef Palate
Recruiting	`NCT06105099` - Effect of Performance-specific Cleft Speech Intervention and Long-term Learning in Children With a Cleft Palate	N/A
Completed	`NCT06075069` - Evaluation of the Effect of Prosthetic Management for Congenital Cleft Lip and Palate Infants on the Middle Ear Function	N/A
Completed	`NCT04384276` - Weigh Easy: Simplifying Home Weight Monitoring for Infants	N/A
Recruiting	`NCT04619030` - Augmented Reality (AR): The Future of "Patient Information Leaflets	N/A
Recruiting	`NCT03065686` - Identification of Genetic Factors Implicated in Orofacial Cleft Using Whole Exome Sequencing	N/A
Completed	`NCT02845193` - Effect of Novel Nasoalveolar Molding Techniques on Parents' Satisfaction and Short Term Treatment Outcomes in Unilateral Cleft Lip and Palate Infants: A Randomized Controlled Trial	N/A
Completed	`NCT03308266` - Electromyographic Analysis of the Masticatory Muscles in Cleft Lip and Palate Children With Temporomandibular Disorders	N/A
Completed	`NCT01932164` - Use of Mesenchymal Stem Cells for Alveolar Bone Tissue Engineering for Cleft Lip and Palate Patients	N/A
Not yet recruiting	`NCT06411444` - Effect of Different Nasal Stent Designs With Nasoalveolar Molding Appliance	N/A
Not yet recruiting	`NCT06292234` - Patient Specific Implant Versus Miniplates for Advancement of Hypoplastic Maxilla	N/A
Recruiting	`NCT05081258` - Influence of Presurgical Orthodontic Molding on the Growth of Newborns With Unilateral Cleft Lip Palate	N/A