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Cleft Lip and Palate clinical trials

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NCT ID: NCT06451276 Not yet recruiting - Clinical trials for Cleft Lip and Palate

The Effectiveness of Adhesive Versus Conventional Nasoalveolar Molding on Children With Unilateral Cleft Lip and Palate

Start date: July 20, 2024
Phase: N/A
Study type: Interventional

The present study will compare the effectiveness of adhesive nasoalveolar molding (GS-NAM) and conventional nasoalveolar molding on the alveolar ridge, nasal, and labial growth in children with unilateral cleft lip and palate. objectives: - 1. Evaluation of the anatomical position of the greater and lesser segments of the maxilla related to a stable midline anatomical point. 2. Evaluation of the nasal symmetry.

NCT ID: NCT06411444 Not yet recruiting - Clinical trials for Cleft Lip and Palate

Effect of Different Nasal Stent Designs With Nasoalveolar Molding Appliance

Start date: May 15, 2024
Phase: N/A
Study type: Interventional

This study is designed to compare 2 different designs of nasal stents in conjunction with nasoalveolar molding appliance regarding the changes in nose and lip esthetics in infants with cleft lip and palate.

NCT ID: NCT06381713 Not yet recruiting - Clinical trials for Cleft Lip and Palate

Effect and Cost-utility of of High Intensity vs. Low Intensity Speech Intervention in Children With Cleft Palate

Start date: August 2024
Phase: N/A
Study type: Interventional

Achieving speech that is understandable and acceptable to others is the key outcome in cleft treatment. Therefore, speech therapy provided by a speech-language pathologist is necessary. This intervention is traditionally provided twice per week for 30 minutes for months or even years by first-line speech-language pathologists. Unfortunately, this low intensity intervention is based on a historical context rather than scientific evidence. This means that current speech therapy knows several shortcomings including poor outcomes, treatment fatigue and high costs related to year-long therapy. Because of these issues, the use of high intensity speech intervention is proposed. Even though solid proof-of-concepts exist for this model, it has not yet found its way into clinical practice. Before this intensity can be implemented and utilized in clinical practice, the effect of this novel program on a larger societal scale must be determined. This project will compare the effect of high intensity and low intensity speech intervention in children with a cleft palate in terms of speech, quality of life, and cost-utility as provided by first-line speech-language pathologists by conducting a large-scale randomized controlled trial. The final goal is to utilize this program in clinical practice and to create awareness of the benefits for children with a cleft palate among stakeholders.

NCT ID: NCT06292234 Not yet recruiting - Clinical trials for Cleft Lip and Palate

Patient Specific Implant Versus Miniplates for Advancement of Hypoplastic Maxilla

Start date: May 1, 2024
Phase: N/A
Study type: Interventional

Distraction osteogenesis is the treatment of choice in management of severe maxillary anteroposterior deficiency allowing for a progressive bone generation and simultaneous expansion of the surrounding scarred soft tissue & better long-term stability & less relapse rate.

NCT ID: NCT06211205 Not yet recruiting - Clinical trials for Cleft Lip and Palate

Effectiveness of a Customized 3D Printed Nostril Retainer Combined With Taping Vs.Taping Only on Enhancing the Nasolabial Esthetics and Maxillary Arch Dimensions in Infants With Unilateral Complete Cleft Lip and Palate.

Start date: January 30, 2024
Phase: N/A
Study type: Interventional

Lip taping was proven as simple, handy technique of PSIO for alveolar molding yielding enhanced maxillary arch dimensions in UCCLP infants. The approach behind this study is to combine this simple step with a digitally designed 3D printed customized nasal molding device to enhance the naslolabial esthetics and maxillary arch dimensions in infants with unilateral complete cleft lip and palate, employing full digital workflow.

NCT ID: NCT05031039 Not yet recruiting - Clinical trials for Cleft Lip and Palate

Skeletal and Dental Maturational Stages in a Sample of Egyptian Subjects With Cleft Lip and Palate Deformity

Start date: September 2021
Phase:
Study type: Observational

The aim of this research is to evaluate the skeletal and dental maturation of cleft lip and palate patients in a sample of Egyptian population using the CVM as indicator for the skeletal maturation and the Demirjian method as indicator for the dental one when compared to a group of Egyptian non-CLP subjects of the same age.

NCT ID: NCT04791813 Not yet recruiting - Clinical trials for Cleft Lip and Palate

Assessment of Maxillary Arch Depth and Width in a Group of Surgically Repaired Unilateral Cleft Lip and Palate Children Versus Normal Children .

Start date: March 2022
Phase:
Study type: Observational

The aim of the present study is to determine the effect of surgically repaired UCLP on dental arch dimensions and the need for orthodontic intervention in comparison with other healthy children , the presence of dental anomalies and the best possible standards of care among this group of Egyptian children.

NCT ID: NCT04236466 Not yet recruiting - Clinical trials for Cleft Lip and Palate

Transverse Dento-skeletal Effects of Two Rapid Palatal Expansion Appliances in Cleft Lip and Palate Patients

Start date: March 2020
Phase: N/A
Study type: Interventional

Aim of the study: to compare the effect of Hyrax appliance and the Haas appliance improving the transverse skeletal and dental dimensions in cleft lip and palate patients during mixed dentition.

NCT ID: NCT03217890 Not yet recruiting - Clinical trials for Cleft Lip and Palate

the Relationship Between Cleft Lip and / or Palate (Different Types) and ABO Blood Groups.

Start date: August 2017
Phase: N/A
Study type: Observational

Direct benefit of the research to assess the relationship between cleft lip and / or palate (different types) and ABO blood groups.

NCT ID: NCT03011489 Not yet recruiting - Clinical trials for Cleft Lip and Palate

Parent's Satisfaction and Evaluation of Postsurgical Outcomes in Unilateral Cleft Lip / Palate Newly Born Infants With / Without Vacuum Formed Nasoalveolar Molding Aligners : A Controlled Clinical Trial

Start date: January 2017
Phase: N/A
Study type: Interventional

Newborns with unilateral cleft lip/ palate will be treated pre-surgically by Vacuum formed aligners in order to evaluate its effect on Nasoalveolar complex.