Cleft; Alveolar Process Clinical Trial
Official title:
Evaluation of Mineralized Plasmatic Matrix Prepared From Allogenic Bone Graft in Alveolar Cleft Closure: A Prospective Randomized, Triple Blinded, Parallel Clinical Trial
The aim of this trial is to figure out the efficiency of Mineralized Plasmatic Matrix prepared from allogenic bone graft on cleft alveolus and oro-nasal fistula closure, adequate bone volume and acceptable density at the site of grafting.MPM might improve the physiological properties of allogenic bone graft and facilitate its handling and application during surgical grafting.This might decrease the need of the second surgical site for harvesting autogenous bone to be grafted with its all complications and hurdles.This trial will help the practitioners in taking the decision of using the MPM prepared from allogenic bone in alveolar cleft closure or not.
Alveolar bone grafting will be performed at 6 to 12 years of age as following :
Group (A):Will undergo grafting with anterior iliac crest bone,(Control group). Group
(B):Will undergo grafting with Mineralized Plasmatic Matrix prepared from allogenic bone
graft (study group).
In all patients, this will be the first bone graft to be placed in the alveolar cleft. All
patients will be monitored clinically and radiographically (by cone beam C.T) for up to 6
months after surgery.
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