Serum Hepcidin, Haemoglobin Level and Iron Status in Chronic Kidney Disease Patients (CKD) With Anaemia

CKD Stage 4 Clinical Trial

Official title:

Association Between Hepcidin, Haemoglobin Level and Iron Status in Stage 4 Chronic Kidney Disease Patients With Anaemia

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT04102319
• Other study ID #: hepcidin,Anemia
• Status: Not yet recruiting
• Start date: October 1, 2019
• Est. completion date: December 1, 2023

Study information

• Verified date: September 2019
• Source: Assiut University
• Contact: Deiaaeldeen Mohamed, master degree
• Phone: +201032997001
• Email: deiaa_1981[@]yahoo.com
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The current study is planned to assess possible relationships of serum hepcidin levels with haemoglobin levels, inflammation and iron statuses in stage 4 CKD patients.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 64
• Est. completion date: December 1, 2023
• Est. primary completion date: October 1, 2022
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Adult patients (>18 years) with anaemia who had CKD stage 4 with glomerular filtration rate (GFR) 15-29 ml/min/1.73 m2

Exclusion Criteria:

• Subjects with blood transfusion within the preceding 3 months. myocardial infarction (MI) history within the preceding 3 months, surgical history within the preceding 3 months, malignancy. Advanced liver cirrhosis. uncontrolled diabetes

Related Conditions & MeSH terms

• CKD Stage 4
• Kidney Diseases
• Renal Insufficiency, Chronic

Intervention

Diagnostic Test:
• serum hepcidin
it is a serum marker

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Assiut University

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	relation between serum hepcidin level and ESR ckd stage 4	measure strength of relation, r, between levels of serum hepcidin and ESR, an inflammation marker	at study entry and then again after 3 months
Primary	relation between serum hepcidin and serum ferritin levels	measure strength of relation, r, between levels of hecidin and ferritin	at study entry and then again after 3 months