The Correlation Between Cirrhotic Cardiomyopathy and Perioperative Cardiovascular Events in Liver Transplantation

Cirrhosis, Liver Clinical Trial

Official title:

Affiliated Hospital of Qingdao University

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT04976764
• Other study ID #: QYFYWZLL26462
• Status: Not yet recruiting
• Start date: August 1, 2021
• Est. completion date: September 1, 2023

Study information

• Verified date: July 2021
• Source: The Affiliated Hospital of Qingdao University
• Contact: shenghua Bi
• Phone: +8618863608195
• Email: bsh112359[@]163.com
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Liver transplantation is an effective treatment for end-stage liver disease. Cardiovascular complications are the common causes of death in liver transplant recipients. The presence of cirrhosis cardiomyopathy has a potential impact on the prognosis of liver transplant recipients. Therefore, it is important to identify the high risk factors with cirrhotic cardiomyopathy before transplantation, so as to intervene earlier and improve the prognosis of patients.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 850
• Est. completion date: September 1, 2023
• Est. primary completion date: August 1, 2022
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 80 Years

Eligibility

Inclusion Criteria:

1. Diagnostic criteria for decompensated liver cirrhosis: according to the guidelines for diagnosis and treatment of liver cirrhosis in 2019;

2. Diagnostic criteria for cirrhotic cardiomyopathy: in accordance with the revised criteria of CCM of international multidisciplinary Alliance for cirrhotic cardiomyopathy in 2019, the preoperative echocardiographic images of all patients were reviewed, and the systolic and diastolic dysfunction of all patients were evaluated.

Exclusion Criteria:

1. the compensatory liver cirrhosis, primary liver cancer without liver cirrhosis

2. Multiple organ transplantation or multiple organ transplantation

3. The preoperative echocardiographic data were not fully recorded, so that the exact diagnosis could not be made

4. There was no follow-up data or baseline data

Related Conditions & MeSH terms

• Cirrhosis, Liver
• Liver Cirrhosis

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
The Affiliated Hospital of Qingdao University

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	perioperative cardiovascular events	there are differences between 2 groups.	2012.1.1-2022.8