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Terlipression Prevent Developing of Acute Kidney Injury During Upper-gastroentestinal Bleeding

Cirrhosis, Liver Clinical Trial

Official title:
The Protection of Telipression on Developing of Acute Kidney Injury in Cirrhotic Patients With Upper-gastroentestinal Bleeding

Clinical Trial Summary

The investigators studied the renal function index level in terlipressin treated cirrhotic patients with upper-gastrointestinal bleeding at different time point.

Clinical Trial Description

54 cirrhotic patients with uppre-gastrointestinal bleeding were entrolled and were distributed into terlipressin group and control group at 1:1 rate. Patients in Terlipressin group received 1mg/6h of terlipressin intravenously for 5 days, and patients in control group recerved 1mg/12h of Somatostatin intravenously for 5 days.

At enrollment, 24h,48h,72,and 1week, the renal function index level( serum creatinine,urine biochemistry and Urinary tubule injury index etc) were tested. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04358016
Study type Interventional
Source Changhai Hospital
Contact
Status Completed
Phase Phase 4
Start date January 1, 2018
Completion date March 1, 2020
View Details
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