Circulatory Function Clinical Trial
Official title:
Preliminary Study on the Changes of Perioperative Circulatory Function in Patients Undergoing Laparoscopic Radical Cystectomy for Bladder Cancer
Verified date | February 2022 |
Source | RenJi Hospital |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
To optimize the perioperative management of patients undergoing laparoscopic radical cystectomy(LPC) for bladder cancer through observation of perioperative changes of Brain Natriuretic Peptide(BNP), stroke volume variation(SVV), central venous pressure(CVP) and the use of transthoracic echocardiography(TTE).
Status | Completed |
Enrollment | 186 |
Est. completion date | December 31, 2019 |
Est. primary completion date | December 31, 2019 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years to 90 Years |
Eligibility | Inclusion Criteria: - undergoing laparoscopic radical cystectomy for bladder cancer - ASA I-II Exclusion Criteria: - Cardiac insufficiency - Hepatic insufficiency - Renal insufficiency |
Country | Name | City | State |
---|---|---|---|
China | Renji Hospital, School of Medicine, Shanghai Jiaotong University, China | Shanghai | Shanghai |
Lead Sponsor | Collaborator |
---|---|
RenJi Hospital |
China,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Brain Natriuretic Peptide(BNP) | To observe the change of BNP perioperatively. | before induction (T1), at the end of operation(T2), at 12 hours (T3) and 24 hours (T4) postoperatively | |
Primary | Central Venous Pressure(CVP) | To observe the change of CVP perioperatively. | before induction (T1),at the end of operation (T2), at 12 hours (T3) and 24 hours (T4) postoperatively | |
Primary | Stroke Volume Variation(SVV) | To observe the change of SVV perioperatively. | before induction (T1), at the end of operation (T2) | |
Primary | Transthoracic Echocardiography | To observe the change of End-diastolic volume(EDV) perioperatively | before induction (T1),at the end of operation (T2), at 12 hours (T3) and 24 hours (T4) postoperatively |