Clinical Trials Logo

Clinical Trial Summary

The purpose of this study is to investigate the level of Circulating Tumor Cells (CTCs) in cancer patients before and after undergoing treatment regimens where the primary treatment modality is radiation therapy (XRT). Specifically, there is interest in the change in CTCs pre- and post- XRT, both in absolute and relative terms.


Clinical Trial Description

CTCs measurements will be taken pre- and post-RT treatment. CTCs measurements will also be taken during treatment. The CTCs measurements from this study will provide essential information for the power and sample size considerations for future translational studies, particularly for those looking to identify biomarkers possibly associated with CTCs and tumor response activity after XRT, and to adequately power more formal statistical comparisons of important associations between CTCs and patient characteristics and outcomes. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT02449837
Study type Observational
Source UNC Lineberger Comprehensive Cancer Center
Contact
Status Completed
Phase
Start date May 2014
Completion date February 20, 2022

See also
  Status Clinical Trial Phase
Recruiting NCT02072616 - Detection of Circulating Tumor Cells for the Diagnostic of Pancreatic Adenocarcinoma. Phase 3
Completed NCT02808884 - Cancer DNA Screening Pilot Study (CANDACE) N/A
Recruiting NCT06068348 - Liquid Biopsy Collection Study
Completed NCT02335151 - CTC Pancreatic Adenocarcinoma Phase 4
Completed NCT01015625 - Primary Operation in SYnchronous meTastasized InVasivE Breast Cancer N/A
Recruiting NCT02602938 - Aspirin on CTCs of Advanced Breast and Colorectal Cancer Phase 2
Completed NCT02499458 - Prospective Validation of Circulating Tumor Cells & Circulating Endothelial Cells as Biomarkers in Renal Cancer
Completed NCT03101046 - Treatment of Metastatic Castrate Resistant Prostate Cancer Patients According to Circulating Tumor Cells Kinetic Phase 2
Recruiting NCT02451384 - According CTC to Compare the Influences of Different Methods to Remove the PDAC N/A
Recruiting NCT01052818 - Therapeutic and Prognostic Impact of Circulating Tumor Cells in Peripheral Blood in Patients With Non Small-cell Lung Cancer N/A
Not yet recruiting NCT04239105 - Detection of Circulating Tumor Cells in Breast Cancer Patients Using a Novel Microfluidic and Raman Spectrum Device
Recruiting NCT03156777 - Application Value of CTCs Detection for Advanced Gastric Cancer Patients N/A
Recruiting NCT02554448 - Detection of CTCs in Stage III Rectal Cancer Patients Undergoing Neoadjuvant Therapy N/A
Completed NCT02345473 - Detection and Clinical Significance of Circulating Cancer Cells in Patient Undergoing Radical Cystectomy N/A
Not yet recruiting NCT04229121 - Clinical Sensitivity Verification Study of Circulating Tumor Cells Gene Mutation Detection From Advanced NSCLC Patients
Completed NCT02955173 - Significance of Circulating Tumor Cells in the Treatment of Gastric and Rectal Cancer N/A
Completed NCT03340844 - Role of CTC´s Spread During Pancreaticoduodenectomy in Patients With Pancreatic and Periampullary Tumors N/A
Active, not recruiting NCT03381326 - CTC, Free DNA, Stem Cells and EMT-related Antigens as Biomarkers of Activity of Cabazitaxel in CRPC.
Completed NCT05502458 - Effect of Propofol and Desflurane on Nucleic Acid of Liver Circulating Tumor Phase 2
Enrolling by invitation NCT04972461 - Therapeutic Response Evaluation by CTC Expansion System