Effects of Light and Exercise on Human Circadian Rhythms and Performance

Circadian Rhythm Clinical Trial

Official title:

Effects of Light and Exercise on Human Circadian Rhythms and Performance

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02747719
• Other study ID #: HFP02802
• Status: Completed
• Phase: N/A
• Start date: April 2016
• Est. completion date: May 31, 2018

Study information

• Verified date: July 2018
• Source: Brigham and Women's Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Both light and exercise are effective countermeasures for space and ground-based crews for circadian phase resetting and alertness levels. The investigators propose to test the combined effects of these two countermeasures to determine whether adding exercise to light stimuli will further improve circadian phase resetting and alertness.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 8
• Est. completion date: May 31, 2018
• Est. primary completion date: May 31, 2017
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 55 Years

Eligibility

Inclusion Criteria:

• healthy by history, physical exam, laboratory studies of blood and urine, and psychological screening

• moderate-intensity exercise for at least 150 minutes per week

Exclusion Criteria:

• color blind

• no prescription medications, except hormonal birth control in females

Related Conditions & MeSH terms

• Circadian Rhythm

Intervention

Behavioral:
• Light and exercise
Exposure to light and exercise

Locations

Country	Name	City	State
United States	Brigham and Women's Hospital	Boston	Massachusetts

Sponsors (2)

Lead Sponsor	Collaborator
Brigham and Women's Hospital	NSBRI

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Circadian Phase	Circadian Phase will be measured using the change in timing of the melatonin rhythm on different days of the protocol. Melatonin will be assayed in blood and/or saliva.	8 days
Secondary	Subjective alertness	Subjective alertness will be measured using the change in values on standardized mood scales on different days of the protocol.	8 days