Glaucoma, Open-Angle Clinical Trial
Official title:
Circadian Variations in Ocular Blood Flow in Glaucomatous and Normal Eyes
After focusing many years only on intraocular pressure (IOP) as the primary risk factor,
recently the impact of ocular blood flow is getting more consideration for the
pathophysiology of glaucoma. The circadian change of intraocular pressure (IOP) is well
investigated, but diurnal variations in ocular blood flow are yet to be evaluated,
especially in glaucomatous eyes.
This study is performed to investigate circadian variation of ocular blood flow assessed by
laser interferometric fundus pulsation amplitude (FPA) and laser Doppler flowmetry (LDF) in
glaucomatous eyes during topical antiglaucoma therapy at 8:00, 12:00, 17:00 and 21:00, to
compare these circadian variation of ocular blood flow in glaucomatous eyes with variations
in healthy eyes and to relate blood flow variations with IOP variations.
n/a
Observational Model: Case Control, Time Perspective: Prospective
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