Circadian Rhythm Disorders Clinical Trial
Official title:
Is Ganglion Cell Thickness the Main Problem in Enuresis Nocturna?
The precise role of the intrinsic circadian regulatory mechanism behind the pathogenesis of enuresis is not fully understood, but in theory, circadian rhythm irregularity may be the primary pathogenic mechanism not only for urinary outflow mechanisms but also for nocturnal bladder function. The proximity between SCN centers that control AVP release, sleep/arousal, voiding, and baroreregulation may provide the basis for circadian rhythm disturbance in one or more of these biological functions. Ganglion cells containing melanopsin pigment in the retina transmit the information they receive from the outside world about the light-dark state to the SCN via the retinohypothalamic pathway. Peripapillary retinal nerve fiber layer (RNFL) thickness, optic nerve head and macula are examined most frequently for the diagnosis of glaucoma and the detection of progression with optical coherence tomography (OCT). If differences in ganglion cell thickness can be detected using OCT in these children, a new avenue in Enuresis Nocturna may be opened.
n/a
Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
NCT04578249 -
Effects of Blocking Blue Light at Night Post CABG, AVR, MVR, CABG AVR, CABG MVR, or SAH
|
N/A | |
Recruiting |
NCT06129942 -
Light Therapy in Parkinson's Disease
|
N/A | |
Recruiting |
NCT06083831 -
The Effect of Sequential Feeding for Circadian Rhythm and Gut Flora Rhythm in Critically Ill Patients
|
||
Recruiting |
NCT05228444 -
Managing Sleep-wake Disruption Due to Hospitalisation: the Circadian Care Project
|
N/A | |
Active, not recruiting |
NCT04953754 -
Melatonin and Vaccine Response, Immunity, and Chronobiology Study
|
N/A | |
Not yet recruiting |
NCT05452096 -
SHIFTPLAN: an RCT Investigating the Effect of a Shift Work Intervention on Fatigue, Sleep and Health.
|
N/A | |
Completed |
NCT01327040 -
Light Sensitization Study
|
N/A | |
Completed |
NCT03331822 -
The Effects of Bright Light Exposure on ICU Nurses
|
N/A | |
Completed |
NCT03646084 -
Sleep and Circadian Intervention Program for Chronic Musculoskeletal Pain
|
N/A | |
Recruiting |
NCT04690504 -
Validation of Circadian Biomarkers in Patients With Sleep Disorders
|
||
Recruiting |
NCT06023654 -
Identifying Circadian Rest-Activity Rhythm Disorders in Patients With Advanced Cancer
|
||
Completed |
NCT03682185 -
The Healthy Patterns Sleep Study
|
Phase 3 | |
Recruiting |
NCT06346613 -
Prevalence and Affecting Factors of Sleep and Circadian Rhythm Disorders in ICU
|
||
Recruiting |
NCT05309577 -
Self-Care for Dementia Caregivers
|
N/A | |
Completed |
NCT04157244 -
The Music, Sleep and Dementia Study
|
N/A | |
Completed |
NCT03468400 -
Evaluation of the Reliability and Validity of a Diagnostic Sleep Disorders Questionnaire
|
||
Recruiting |
NCT04063332 -
Functionality of Endogenous Biological Clock in Sepsis
|
||
Recruiting |
NCT06329479 -
A Feasibility Trial for Circadian Rest-activity Rhythm Disorders in Cancer (RALI)
|
N/A | |
Recruiting |
NCT04401189 -
The Role of Circadian Rhythms in Cancer-Related Symptoms
|
||
Completed |
NCT03684460 -
Daytime Bright Light, Circadian Abnormalities, and Delirium in Medical ICU Patients
|
N/A |