To Compare Intravenous and Oral Hydration of the Prevention for CIN in Elderly Patients Undergoing Intravenous CECT

CIN Clinical Trial

— CINOECT  

Official title:

To Compare Intravenous and Oral Hydration of the Prevention for Contrast-induced Nephropathy in Elderly Patients Undergoing Intravenous Contrast-enhanced Computed Tomography： A Multi-center Randomized Control Trail

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT03872739
• Other study ID #: 201704020124
• Status: Recruiting
• Phase: N/A
• Start date: October 8, 2016
• Est. completion date: October 2021

Study information

• Verified date: March 2019
• Source: Guangdong Academy of Medical Sciences
• Contact: Danqing Yu, Doctor
• Phone: 13631349257
• Email: gdydq100[@]126.com
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

To Compare Intravenous and Oral Hydration of the Prevention for Contrast-induced Nephropathy in Elderly Patients Undergoing Intravenous Contrast-enhanced Computed Tomography.

Description:

The prospective multicenter randomized controlled clinical research discusses the comparison of oral and intravenous hydration for prevention of contrast-induced nephropathy in elderly patients with enhanced computed tomography, establishing a simple hydration proposal.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 1368
• Est. completion date: October 2021
• Est. primary completion date: June 30, 2021
• Accepts healthy volunteers: No
• Gender: All
• Age group: 65 Years and older

Eligibility

Inclusion Criteria:

• Age>21

• informed consent

• Undergoing Intravenous Contrast-enhanced Computed Tomography

Exclusion Criteria:

• CT enhancement was not performed;

• Dialysis treatment of patients with end-stage renal failure or heart, kidney transplantation;

• Exposure to radioactive contrast medium within 48 hours prior to or within 72 hours of examination;

• Acute decompensated heart failure;

• Allergic to radioactive contrast agent;

• Be subjected to life - threatening trauma;

• Severe infection;

• Surgery was performed within 2 days of CT examination.

• Combined with multiple myeloma, urinary obstruction, aortic dissection

• Can cause acute kidney injury disease;

• Use of aminoglycosides and other nephrotoxic drugs 2 weeks before.

Related Conditions & MeSH terms

• CIN

Intervention

Procedure:
• enhanced computed tomography
undergoing enhanced computed tomography

Locations

Country	Name	City	State
China	Guangdong provincial people's hospital	Guanzhou	Guangdong

Sponsors (1)

Lead Sponsor	Collaborator
Yu Danqing

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	CIN	Compared with before examination, the increase of serum creatinine conforms to the diagnostic criteria of contrast induced nephropathy.	72hours