Cigarette Smoking Clinical Trial
— MUSC-R 3aOfficial title:
Examining the Generality of Laboratory-based Findings and Their Moderators Using Diverse Samples From the International Tobacco Control (ITC) Policy Evaluation Project Cohorts - Study 3a
This study will investigate the relative appeal (abuse liability) of novel tobacco products, how the appeal is modulated by relative price, user type, and how novel products may substitute for one another.
Status | Not yet recruiting |
Enrollment | 456 |
Est. completion date | September 16, 2024 |
Est. primary completion date | September 16, 2024 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 21 Years and older |
Eligibility | Inclusion Criteria: - From CA, US, or EN - At least 21 years old - Smoking daily - Smoking mostly or about equal amounts of factory-made cigarettes - Does not currently vape (for exclusive smokers only) - Vapes Daily (for dual users only) Exclusion Criteria: - There will be no additional exclusion criteria for this study. |
Country | Name | City | State |
---|---|---|---|
United States | Fralin Biomedical Research Institute | Roanoke | Virginia |
Lead Sponsor | Collaborator |
---|---|
Virginia Polytechnic Institute and State University | Medical University of South Carolina, National Cancer Institute (NCI), University of Waterloo |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Cigarette demand | Participants will complete purchasing trials in an Experimental Tobacco Marketplace (ETM) with cigarettes increasing in price. Other product prices in the ETM will depend on the experimental condition. The degree to which other nicotine/tobacco products substitute for conventional cigarettes as a function of novel product (e.g. nicotine vaping products, heated tobacco products, nicotine pouch products) prices will be assessed.
To obtain dependent measures of demand, participants' purchasing of the price-manipulated commodity in the ETM task will be fit to a modified exponential equation to quantify the relationship between the price of each commodity and purchasing: Q=Q0*10k(exp(-aQ0C)-1) where Q is purchasing of the commodity, C is the price, Q0 is the derived initial purchasing without cost constraints (demand intensity), k is the span of the function in logarithmic units, and a is the demand elasticity. |
1 day | |
Primary | Nicotine/tobacco products substitution | Participants will complete purchasing trials in an Experimental Tobacco Marketplace (ETM) with cigarettes increasing in price. Other product prices in the ETM will depend on the experimental condition. The degree to which other nicotine/tobacco products substitute for conventional cigarettes as a function of novel product (e.g. nicotine vaping products, heated tobacco products, nicotine pouch products) prices will be assessed.
To obtain estimates of substitution of price-constant products in the different ETM conditions, the investigators will use ordinary least squares regression to model the relationship of the price-manipulated product to predict total quantity purchased of the price-constant product. |
1 day |
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