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Menthol, Inflammation, and Nicotine Transition Study — MINT  

Cigarette Smoking Clinical Trial

Official title:
Effect of Menthol to Non-Menthol Cigarette Switching on Subclinical Inflammatory Biomarkers of Cardiovascular Health: Simulating a Menthol Cigarette Ban

Clinical Trial Summary

This study will focus on examining the potential impact of menthol flavoring in cigarettes on biomarkers of systemic inflammation as a subclinical indicator of cardiovascular disease risk.

Clinical Trial Description

The goal of this study is to examine how switching from menthol (MC) to non-menthol (NMC) cigarette smoking may impact biomarkers of systemic inflammation, smoking behavior, and subjective responses related to smoking. MC smokers (N=68) will be recruited for a five-week study, with one-week of baseline of MC smoking (Phase 1), followed by four weeks of switching to study-provided, brand-matched NMCs (Phase 2). Biomarkers of systemic inflammation and tobacco exposure will be analyzed from blood samples before, during, and after switching for four weeks (baseline, week 1, week 3, and week 5). Ecological momentary assessment methods will also be gathered to measure patterns of smoking and smoking-related subjective responses (affect, craving). ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06232447
Study type Interventional
Source Rosalind Franklin University of Medicine and Science
Contact Nancy C Jao, PhD
Phone 847-578-8747
Email nancy.jao@rosalindfranklin.edu
Status Recruiting
Phase N/A
Start date March 26, 2024
Completion date February 2026
View Details
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