Clinical Trial Details
— Status: Completed
Administrative data
NCT number |
NCT04472715 |
Other study ID # |
00007555 |
Secondary ID |
|
Status |
Completed |
Phase |
N/A
|
First received |
|
Last updated |
|
Start date |
January 5, 2020 |
Est. completion date |
December 5, 2020 |
Study information
Verified date |
July 2021 |
Source |
Alexandria University |
Contact |
n/a |
Is FDA regulated |
No |
Health authority |
|
Study type |
Interventional
|
Clinical Trial Summary
follicular unit extraction as a method of hair transplantation in cicatricial alopecia
Description:
The study will include 20 patients with cicatrical alopecia.Patients will be randomly
assigned into two groups:Group (A):include ten patients will undergo (FUE) alone.
Group (B): include ten patients will undergo(FUE) and (PRP).3-Surgical technique:
- Preoperative Investigations including complete blood count, coagulation profile and
hepatitis viral markers.
1-Group(A): will undergo (FUE)
- Washing the scalp with antiseptic shampoo before the procedure.
- Tumuscentanaesthesia:The donor area is anesthetized with a lidocaine 1% solution diluted
with 20 cc saline in addition to adrenaline.
- Creation of micropunches(0.7-1 mm) using micromotor.
- After removal of the punch,the follicular unit is extracted with Jweler's forceps.
- Extracted grafts are then placed on chilled saline gauze for maximum four hours until
ready for transplantation.
- The recipient area is prepared with rectangular scalpel blades 1mm or hypodermic blades
0.9 mm.
- Implantation using fine tipped jweler's forceps.
- Finally, receptor and donor areas will be softly cleansed with saline and crepe bandage
is applied.
2-Group (B): FUE+PRP
- The same procedure will be done but grafts will be placed in Prp solution.
- Prp session one week before transplantation then monthly for 3 monthes after (FUE).
- Preparation of PRP
- 10 cc blood will be aspirated in test tube contained a modified solution of
anticoagulant,called acid-citrate-dextrose type (ACDA), in which the physiological pH
will reached to preserve the platelet integrity.
- The first spin of whole blood sample will be at 2500 rpm for 4 minutes
- The second spin at 4000 for 20 minutes for obtained plasma.
- Platelets are separated as a pellet at the bottom of the tube from platelet-poor plasma
(PPP) above. The platelet-rich pellet is resuspended in remaining amount of plasma. The
resulting suspension is used as PRP.
- Prp is injected in the recipient area. 4-Follow up:
- Follow up clinically by digital photographs and trichoscopy 1 week after operation,
after 3 months and after 6 months.