Chronic Venous Insufficiency Clinical Trial
Official title:
VAP-PRO-C6. Effectiveness and Tolerability of Venoactive Drugs in Combination Therapy and Their Effect on the Overall Treatment Outcomes in Patients With Chronic Venous Diseases of CEAP Classes C6 in Real Clinical Practice
The VAP-PRO-C6 is a Russian multicenter observational program to be implemented at the routine visits and assessments. The program will include patients with chronic venous disease of CEAP classes C6. This program is planned to be carried out in Russia in 2021-2022.
Aim of the program is to describe effectiveness and tolerability of systemic pharmacotherapy as a part of combination therapy and its effect on the overall treatment outcomes in patients with venous ulcers (CEAP classes C6) treated in real clinical settings. The planned number of patients is 350. The inclusion period lasts for 6 months. The treatment will be consistent with routine clinical practice, local label for the medical use of drugs and the specific clinical situation. The following objective methods will be used to assess the changes in the skin condition: - measurement of the area of reference ulcer (using LesionMeter*) before and after the treatment; - changes in status localis. - The presence and location of venous reflux and/or occlusion. The study does not implicate any intervention to routine management of patients with chronic venous disease (CVD). In particular, in this study the parameters that are usually evaluated during the examination of patients with classes C6 CVD (CEAP) will be recorded. Special attention will be paid to evaluating changes of the area of referent VU using objective methods (measuring ulcer area using LesionMeter, time to ulcer healing). - LesionMeter is a generally available tool for measuring the venous ulcer area. ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Terminated |
NCT02462096 -
A Feasibility Study of the ReLeaf Catheter System
|
N/A | |
Enrolling by invitation |
NCT05504070 -
Venclose digiRF System Post Market Study
|
N/A | |
Completed |
NCT05507346 -
A Clinical Study to Evaluate the Effectiveness of a Novel Portable Non-Pneumatic Active Compression Device vs. an Advanced Pneumatic Compression Device for Treating Lower Extremity Lymphedema
|
N/A | |
Recruiting |
NCT05622500 -
Best Endovenous Treatment, Including STenting, Versus Non-endovenous Treatment in Chronic Proximal Deep Venous Disease
|
N/A | |
Completed |
NCT03283800 -
Copper Impact on Venous Insufficiency and Lipodermatosclerosis
|
N/A | |
Completed |
NCT02236338 -
Radiofrequency Ablation vs Laser Ablation of the Incompetent Greater Saphenous Vein
|
Phase 4 | |
Completed |
NCT01501188 -
Efficacy Study of Kinesio Taping to Treat Muscular and Joint Problems in Chronic Venous Insufficiency
|
Phase 1 | |
Terminated |
NCT02248740 -
Radiofrequency Ablation vs. Laser Ablation of the Incompetent Small Saphenous Vein
|
Phase 4 | |
Recruiting |
NCT05982405 -
Long-term Effects of Inspiratory Muscle Training in Chronic Venous Insufficiency
|
N/A | |
Completed |
NCT05383469 -
Efficacy of Active Versus Passive Methods in Chronic Venous Insufficiency
|
N/A | |
Completed |
NCT06238791 -
Plantar Pressure Analysis and Foot Biomechanics in Lipedema and Chronic Venous Disease
|
||
Withdrawn |
NCT02559427 -
SPA Therapy in the Treatment of Sleep Apnea Syndrome
|
N/A | |
Completed |
NCT02346058 -
Efficacy and Safety of Esarin Gel in Chronic Venous Insufficiency and Varicose Veins
|
Phase 4 | |
Active, not recruiting |
NCT05926830 -
Extracorporeal Flow Abolition in Relation With Primary Insufficiency of Great Saphenous Veins (GSV) Using High Intensity Focused Ultrasound (HIFU) Generated by Sonovein: A Multi Center Prospective Pivotal Study
|
N/A | |
Withdrawn |
NCT05047302 -
Investigation of Femoropopliteal In Situ Valve Formation With the InterVene System-Canada
|
N/A | |
Active, not recruiting |
NCT04339075 -
Registry to Investigate the Efficacy and Safety of VenaBlock VeIn SEaling System for VaRicose Veins in SingApore
|
||
Active, not recruiting |
NCT04580160 -
Venous Stent for the Iliofemoral Vein Investigational Clinical Trial Using the DUO Venous Stent System
|
N/A | |
Not yet recruiting |
NCT02927483 -
Study to Assess the Efficacy and Safety of Endolex Forte VErsus Diosmin and Hesperidin in Reducing VeNous Insufficiency
|
Phase 3 | |
Completed |
NCT02015221 -
Evaluation of a Dual Action Pneumatic Compression Device: Patient Ease of Use and Comfort
|
N/A | |
Completed |
NCT02050061 -
Chronic Venous Insufficiency; Impact of Compression Stockings on Quality of Life
|
N/A |